Pallidin Protein (full length) (His tag)
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- Target See all Pallidin (PLDN) Proteins
- Pallidin (PLDN) (Pallidin Homolog (PLDN))
- Protein Type
- Recombinant
- Protein Characteristics
- full length
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Pallidin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
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- Comment
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Synonyms: pallidin, HPS9, PA, PALLID
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM DTT, 10% glycerol, 100 mM NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- Pallidin (PLDN) (Pallidin Homolog (PLDN))
- Alternative Name
- PLDN (PLDN Products)
- Synonyms
- CG14133 Protein, Dmel\\CG14133 Protein, LOC100226487 Protein, pldn Protein, BLOS6 Protein, HPS9 Protein, PA Protein, PALLID Protein, PLDN Protein, Pldn Protein, BLOC-1 Protein, Stx13bp1 Protein, pa Protein, pallidin Protein, CG14133 gene product from transcript CG14133-RB Protein, biogenesis of lysosomal organelles complex 1 subunit 6 Protein, pallidin homolog (mouse) Protein, biogenesis of lysosomal organelles complex-1, subunit 6, pallidin Protein, Pallidin Protein, BLOC1S6 Protein, pldn Protein, Bloc1s6 Protein
- Background
- PLDN (Pallidin) may play a role in intracellular vesicle trafficking. It interacts with Syntaxin 13 which mediates intracellular membrane fusion. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This protein involved in the development of lysosome-related organelles, such as melanosomes and platelet-dense granules. PLDN has been shown to interact with BLOC1S1, STX12, Dysbindin, CNO, BLOC1S2, MUTED and SNAPAP. Recombinant human PLDN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 21.9kDa (192aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- NCBI Accession
- NP_036520
- Pathways
- Synaptic Vesicle Exocytosis
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