PPM1G Protein (AA 317-546) (His tag)
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- Target See all PPM1G Proteins
- PPM1G (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 317-546
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PPM1G protein is labelled with His tag.
- Purpose
- Recombinant Human Protein Phosphatase 1G/PP1MG (C-6His)
- Sequence
- MEGKEEPGSD SGTTAVVALI RGKQLIVANA GDSRCVVSEA GKALDMSYDH KPEDEVELAR IKNAGGKVTM DGRVNGGLNL SRAIGDHFYK RNKNLPPEEQ MISALPDIKV LTLTDDHEFM VIACDGIWNV MSSQEVVDFI QSKISQRDEN GELRLLSSIV EELLDQCLAP DTSGDGTGCD NMTCIIICFK PRNTAELQPE SGKRKLEEVL STEGAEENGN SDKKKKAKRD LEHHHHHH
- Characteristics
- Recombinant Human Protein Phosphatase 1G/PP1MG is produced with our E. coli expression system. The target protein is expressed with sequence (Met317-Asp546) of Human PPM1G.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PPM1G Protein
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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G) (AA 1-546) protein (GST tag)
PPM1G Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G) (AA 1-546) protein (His tag)PPM1G Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PPM1G Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G) (Transcript Variant 1) protein (His tag)PPM1G Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PPM1G Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 25 mM TrisHCl, 1 mM DTT, 1 mM EDTA, 2 mM ß-ME, 20 % Glycerol, pH 7.5.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- PPM1G (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1G (PPM1G))
- Alternative Name
- ppm1g (PPM1G Products)
- Synonyms
- AI385652 Protein, Fin13 Protein, PP2CG Protein, PP2CGAMMA Protein, PPP2CG Protein, protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform Protein, protein phosphatase, Mg2+/Mn2+ dependent 1G Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1G Protein, Ppm1g Protein, PPM1G Protein
- Background
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Protein Phosphatase 1G (PP1MG) is a cytoplasmic protein that belongs to the PP2C family. PPM1G is widely expressed, it is abundant in testis, skeletal muscle, and heart. PPM1G is a negative regulator of cell stress response pathways. PPM1G is responsible for the dephosphorylation of Pre-mRNA splicing factors, an important factor for the formation of functional spliceosome. PPM1G also plays a role in regulating cell cycle progression.
Alternative Names: Protein Phosphatase 1G, Protein Phosphatase 1C, Protein Phosphatase 2C Isoform Gamma, PP2C-Gamma, Protein Phosphatase Magnesium-Dependent 1 Gamma, PPM1G, PPM1C - Molecular Weight
- 26.15 kDa
- UniProt
- O15355
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