BNP Protein (AA 27-134) (His tag)
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- Target See all BNP Proteins
- BNP (Brain Natriuretic Peptide (BNP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-134
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BNP protein is labelled with His tag.
- Purpose
- Recombinant Human Brain Natriuretic Peptide/BNP (His27-His134, N-6His)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MHPLGSPGSA SDLETSGLQE QRNHLQGKLS ELQVEQTSLE PLQESPRPTG VWKSREVATE GIRGHRKMVL YTLRAPRSPK MVQGSGCFGR KMDRISSSSG LGCKVLRRH
- Characteristics
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Recombinant Human Brain Natriuretic Peptide/BNP (His27-His134, N-6His)
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product BNP Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, 1 mM DTT, 20 % Glycerol, pH 7.4.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- BNP (Brain Natriuretic Peptide (BNP))
- Alternative Name
- Brain Natriuretic Peptide (BNP Products)
- Synonyms
- bnp Protein, BNP1 Protein, NPPB Protein, BNP Protein, Bnf Protein, AA408272 Protein, B-type natriuretic peptide Protein, natriuretic peptide B Protein, natriuretic peptide type B Protein, nppb Protein, NPPB Protein, Nppb Protein
- Background
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Recombinant Human Natriuretic Peptides B/NPPB is produced with our E. coli expression system. The target protein is expressed with sequence (His27-His134) of Human NPPB.
Human Natriuretic peptides B acts as a cardiac hormone, it is associated with many biological actions, such as diuresis, natriuresis, vasorelaxation, which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water, improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3. - Molecular Weight
- 14.2 kDa
- UniProt
- P16860
- Pathways
- Hormone Activity
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