LAIR2 Protein (AA 22-152) (His tag)
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- Target See all LAIR2 Proteins
- LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-152
- Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This LAIR2 protein is labelled with His tag.
- Purpose
- Recombinant Human LAIR-2/CD306 (C-6His)
- Sequence
- QEGALPRPSI SAEPGTVISP GSHVTFMCRG PVGVQTFRLE REDRAKYKDS YNVFRLGPSE SEARFHIDSV SEGNAGLYRC LYYKPPGWSE HSDFLELLVK ESSGGPDSPD TEPGSSAGTV PGTEASGFDA PVDHHHHHH
- Characteristics
- Recombinant Human Leukocyte-Associated Immunoglobulin-Like Receptor 2/LAIR2 produced by transfected human cells is a secreted protein with sequence (Gln22-Pro152) of Human LAIR2 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product LAIR2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
- Alternative Name
- lair2 (LAIR2 Products)
- Synonyms
- CD306 Protein, leukocyte associated immunoglobulin like receptor 2 Protein, LAIR2 Protein
- Sub Type
- Fusionprotein
- Background
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Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) is a secreted, 131 amino acid protein that contains one Ig-like C2 type domain, making it a member of the Ig superfamily. When compared to LAIR-1, its transmembrane counterpart, it shares 83% amino acid identity across the signal sequence and extracellular domains, although one is secreted and one is membrane-bound, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles. This suggests that LAIR-2 may compete with LAIR-1 for ligand binding. A 114 amino acid alternate splice form of LAIR-2 is truncated at the C terminus, but retains the entire Ig domain. The expression profile of these splice forms, and the presence of orthologs in other species, have not been reported.
Alternative Names: Leukocyte-Associated Immunoglobulin-Like Receptor 2, LAIR-2, CD306, LAIR2 - Molecular Weight
- 15.1 kDa
- UniProt
- Q6ISS4
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