Kallikrein 6 Protein (KLK6) (AA 17-244) (His tag)
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- Target See all Kallikrein 6 (KLK6) Proteins
- Kallikrein 6 (KLK6)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 17-244
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Kallikrein 6 protein is labelled with His tag.
- Purpose
- Recombinant Human Kallikrein 6/KLK6/Neurosin (C-6His)
- Sequence
- EEQNKLVHGG PCDKTSHPYQ AALYTSGHLL CGGVLIHPLW VLTAAHCKKP NLQVFLGKHN LRQRESSQEQ SSVVRAVIHP DYDAASHDQD IMLLRLARPA KLSELIQPLP LERDCSANTT SCHILGWGKT ADGDFPDTIQ CAYIHLVSRE ECEHAYPGQI TQNMLCAGDE KYGKDSCQGD SGGPLVCGDH LRGLVSWGNI PCGSKEKPGV YTNVCRYTNW IQKTIQAKVD HHHHHH
- Characteristics
- Recombinant Human Kallikrein 6 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Glu17-Lys244) of Human KLK6 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product KLK6 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 5 mM HCl, 150 mM NaCl.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- Kallikrein 6 (KLK6)
- Alternative Name
- neurosin (KLK6 Products)
- Synonyms
- Bssp Protein, Klk7 Protein, PRSS18 Protein, PRSS9 Protein, SP59 Protein, hK6 Protein, Prss9 Protein, AI849898 Protein, BSP Protein, Klk29 Protein, MSP Protein, Prss18 Protein, neurosin Protein, kallikrein related peptidase 6 Protein, kallikrein related-peptidase 6 Protein, kallikrein-6 Protein, KLK6 Protein, Klk6 Protein, LOC100716801 Protein
- Sub Type
- Fusionprotein
- Background
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Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
Alternative Names: Kallikrein-6, Neurosin, Protease M, SP59, Serine Protease 18, Serine Protease 9, Zyme, KLK6, PRSS18, PRSS9 - Molecular Weight
- 26.17 kDa
- UniProt
- Q92876
- Pathways
- Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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