Kallikrein 1 Protein (KLK1) (AA 19-262) (His tag)
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- Target See all Kallikrein 1 (KLK1) Proteins
- Kallikrein 1 (KLK1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-262
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Kallikrein 1 protein is labelled with His tag.
- Purpose
- Recombinant Human Kallikrein 1/KLK1 (C-6His)
- Sequence
- PPIQSRIVGG WECEQHSQPW QAALYHFSTF QCGGILVHRQ WVLTAAHCIS DNYQLWLGRH NLFDDENTAQ FVHVSESFPH PGFNMSLLEN HTRQADEDYS HDLMLLRLTE PADTITDAVK VVELPTQEPE VGSTCLASGW GSIEPENFSF PDDLQCVDLK ILPNDECKKV HVQKVTDFML CVGHLEGGKD TCVGDSGGPL MCDGVLQGVT SWGYVPCGTP NKPSVAVRVL SYVKWIEDTI AENSVDHHHH HH
- Characteristics
- Recombinant Human Kallikrein-1/KLK1 produced by transfected human cells is a secreted protein with sequence (Pro19-Ser262) of Human KLK1 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product KLK1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 2 mM CaCl2, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- Kallikrein 1 (KLK1)
- Alternative Name
- kallikrein-1 (KLK1 Products)
- Synonyms
- KLKR Protein, Klk6 Protein, hK1 Protein, klkr Protein, kallikrein Protein, 0610007D04Rik Protein, Kal Protein, Klk1b6 Protein, mGk-6 Protein, kallikrein 1 Protein, kallikrein 1 L homeolog Protein, KLK1 Protein, klk1.L Protein, LOC100101620 Protein, Klk1 Protein
- Sub Type
- Fusionprotein
- Background
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Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The function of KLK1 is to cleave Kininogen in order to release the vasoactive Kinin peptide (Lysyl-Bradykinin or Bradykinin). The Kinin peptide controls blood pressure reduction, vasodilation, smooth muscle relaxation and contraction, pain induction and inflammation. KLK1 also plays a role in angiogensis and tumorigenesis.
Alternative Names: Kallikrein-1, Kidney/Pancreas/Salivary Gland Kallikrein, Tissue Kallikrein, KLK1 - Molecular Weight
- 28.15 kDa
- UniProt
- P06870
- Pathways
- Complement System
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