IGFBP4 Protein (AA 22-258) (His tag)
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- Target See all IGFBP4 Proteins
- IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-258
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This IGFBP4 protein is labelled with His tag.
- Purpose
- Recombinant Human Insulin-Like Growth Factor-Binding Protein 4/IGFBP-4 (C-6His)
- Sequence
- DEAIHCPPCS EEKLARCRPP VGCEELVREP GCGCCATCAL GLGMPCGVYT PRCGSGLRCY PPRGVEKPLH TLMHGQGVCM ELAEIEAIQE SLQPSDKDEG DHPNNSFSPC SAHDRRCLQK HFAKIRDRST SGGKMKVNGA PREDARPVPQ GSCQSELHRA LERLAASQSR THEDLYIIPI PNCDRNGNFH PKQCHPALDG QRGKCWCVDR KTGVKLPGGL EPKGELDCHQ LADSFREVDH HHHHH
- Characteristics
- Recombinant Human Insulin-Like Growth Factor-Binding Protein 4/IGFBP-4 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (D22-E258) of Human IGFBP4 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product IGFBP4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))
- Alternative Name
- igfbp-4 (IGFBP4 Products)
- Synonyms
- IGFBP4 Protein, igfbp4 Protein, BP-4 Protein, HT29-IGFBP Protein, IBP4 Protein, IGFBP-4 Protein, AI875747 Protein, Deb2 Protein, IGF-BP4 Protein, IBP-4 Protein, insulin like growth factor binding protein 4 Protein, insulin-like growth factor-binding protein 4 Protein, insulin-like growth factor binding protein 4 Protein, IGFBP4 Protein, LOC100136305 Protein, LOC100194498 Protein, igfbp4 Protein, Igfbp4 Protein
- Sub Type
- Fusionprotein
- Background
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IGFBP-4, whose full name is insulin-like growth factor-binding protein 4, is induced by forskolin and N6, O2’dibutyryl sdenosine 3’, or 5’-cyclic monophosphate. It contains IGFBP N-terminal domain and thyroglobulin type-1 domain, and can bind IGF2. The IGF-binding proteins can prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.
Alternative Names: Insulin-Like Growth Factor-Binding Protein 4, IBP-4, IGF-Binding Protein 4, IGFBP-4, IGFBP4, IBP4 - Molecular Weight
- 27.01 kDa
- UniProt
- P22692
- Pathways
- WNT Signaling, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process
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