AKR1C2 Protein (AA 1-323)
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- Target See all AKR1C2 Proteins
- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-323
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human Aldo-Keto Reductase 1C2/AKR1C2
- Sequence
- MDSKYQCVKL NDGHFMPVLG FGTYAPAEVP KSKALEAVKL AIEAGFHHID SAHVYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSNSH RPELVRPALE RSLKNLQLDY VDLYLIHFPV SVKPGEEVIP KDENGKILFD TVDLCATWEA MEKCKDAGLA KSIGVSNFNH RLLEMILNKP GLKYKPVCNQ VECHPYFNQR KLLDFCKSKD IVLVAYSALG SHREEPWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTS EEMKAIDGLN RNVRYLTLDI FAGPPNYPFS DEY
- Characteristics
- Recombinant Human Aldo-Keto Reductase Family 1 Member C2/AKR1C2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Tyr323) of Human AKR1C2.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product AKR1C2 Protein
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Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-256) protein (His tag)
AKR1C2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 224-323) protein (GST tag)AKR1C2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-323) protein (GST tag)AKR1C2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-323), (full length) protein (His-SUMO Tag)AKR1C2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Aldo-keto Reductase Family 1, Member C2 (AKR1C2) protein (Myc-DYKDDDDK Tag)AKR1C2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, pH 8.0.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
- Alternative Name
- DDH2 (AKR1C2 Products)
- Synonyms
- AKR1C-pseudo Protein, BABP Protein, DD Protein, DD2 Protein, DDH2 Protein, HAKRD Protein, HBAB Protein, MCDR2 Protein, SRXY8 Protein, Akr1c21 Protein, aldo-keto reductase family 1 member C2 Protein, aldo-keto reductase family 1, member C2 Protein, AKR1C2 Protein, Akr1c2 Protein
- Background
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Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-alpha/5-beta-Steroid Reductases to convert Steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-alpha-Dihydrotestosterone (5-alpha-DHT) to 5-alpha-Androstane-3-alpha, 17-beta-diol (3-alpha-diol).
Alternative Names: Aldo-Keto Reductase Family 1 Member C2, 3-Alpha-HSD3, Chlordecone Reductase Homolog HAKRD, Dihydrodiol Dehydrogenase 2, DD-2, DD2, Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein, DD/BABP, Trans-1,2-Dihydrobenzene-1,2-Diol Dehydrogenase, Type III 3-Al - Molecular Weight
- 36.74 kDa
- UniProt
- P52895
- Pathways
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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