CDO1 Protein (AA 1-200) (His tag)
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- Target See all CDO1 Proteins
- CDO1 (Cysteine Dioxygenase, Type I (CDO1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-200
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CDO1 protein is labelled with His tag.
- Purpose
- Recombinant Human Cysteine Dioxygenase Type 1/CDO1 (N-6His)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MEQTEVLKPR TLADLIRILH QLFAGDEVNV EEVQAIMEAY ESDPTEWAMY AKFDQYRYTR NLVDQGNGKF NLMILCWGEG HGSSIHDHTN SHCFLKMLQG NLKETLFAWP DKKSNEMVKK SERVLRENQC AYINDSVGLH RVENISHTEP AVSLHLYSPP FDTCHAFDQR TGHKNKVTMT FHSKFGIRTP NATSGSLENN
- Characteristics
- Recombinant Human Cysteine Dioxygenase Type 1/CDO1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Asn200) of Human CDO1 fused with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CDO1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 1 mM DTT, 10 % Glycerol, pH 8.0.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- CDO1 (Cysteine Dioxygenase, Type I (CDO1))
- Alternative Name
- Cysteine Dioxygenase Type 1 (CDO1 Products)
- Synonyms
- 1300002L19Rik Protein, Cdo Protein, D18Ucla3 Protein, cysteine dioxygenase, type I Protein, cysteine dioxygenase 1, cytosolic Protein, cysteine dioxygenase type 1 Protein, NAEGRDRAFT_80458 Protein, Cdo1 Protein, CDO1 Protein
- Sub Type
- Fusionprotein
- Background
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Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pancreas. CDO1 can also be detected in hepatoblastoma HepG2 cells. CDO1 catalyzes the conversion of L-cysteine to cysteine sulfinic acid by incorporation of dioxygen. CDO1 is a vital regulator of cellular cysteine concentrations and has an essential role in maintaining the hepatic concentration of intracellular free cysteine within a proper narrow range. CDO1 is able to alter intracellular cysteine levels and glutathione levels.
Alternative Names: Cysteine Dioxygenase Type 1, Cysteine Dioxygenase Type I, CDO, CDO-I, CDO1 - Molecular Weight
- 25.1 kDa
- UniProt
- Q16878
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