CCL26 Protein (AA 24-94)
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- Target See all CCL26 Proteins
- CCL26 (Chemokine (C-C Motif) Ligand 26 (CCL26))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-94
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human C-C Motif Chemokine 26/CCL26 (24-94)
- Sequence
- MTRGSDISKT CCFQYSHKPL PWTWVRSYEF TSNSCSQRAV IFTTKRGKKV CTHPRKKWVQ KYISLLKTPK QL
- Characteristics
- Recombinant Human C-C Motif Chemokine 26/CCL26 (24-94) is produced with our E. coli expression system. The target protein is expressed with sequence (Thr24-Leu94) of Human CCL26.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CCL26 Protein
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Chemokine (C-C Motif) Ligand 26 (CCL26) protein
CCL26 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Chemokine (C-C Motif) Ligand 26 (CCL26) (AA 24-94) protein (GST tag)CCL26 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 26 (CCL26) (AA 1-94) protein (GST tag)CCL26 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 1 mM EDTA, 20 % Glycerol, pH 9.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- CCL26 (Chemokine (C-C Motif) Ligand 26 (CCL26))
- Alternative Name
- eotaxin-3 (CCL26 Products)
- Synonyms
- CCL26 Protein, IMAC Protein, MIP-4a Protein, MIP-4alpha Protein, SCYA26 Protein, TSC-1 Protein, Ccl26l Protein, C-C motif chemokine ligand 26 Protein, chemokine (C-C motif) ligand 26 Protein, CCL26 Protein, Ccl26 Protein
- Background
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Chemokine Ligand 26 protein (CCL26) is a novel small cytokine belonging to the CC chemokine family which is involved in immunoregulatory and inflammatory processes. CCL26 is constitutively expressed in thymus, but only transiently expressed in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL26, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The full-length cDNA for CCL26 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues. Both the 71 and 68 amino acid residue variants of recombinant CCL26 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line. Unlike most other CC chemokines, CCL26 maps to human chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. CCL26 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7.
Alternative Names: C-C Motif Chemokine 26, CC Chemokine IMAC, Eotaxin-3, Macrophage Inflammatory Protein 4-Alpha, MIP-4-Alpha, Small-Inducible Cytokine A26, Thymic Stroma Chemokine-1, TSC-1, CCL26, SCYA26 - Molecular Weight
- 8.53 kDa
- UniProt
- Q9Y258
- Pathways
- Regulation of Actin Filament Polymerization
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