BTN1A1 Protein (AA 27-242) (His tag)
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- Target See all BTN1A1 Proteins
- BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-242
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This BTN1A1 protein is labelled with His tag.
- Purpose
- Recombinant Human Butyrophilin 1A1/BTN1A1 (C-6His)
- Sequence
- APFDVIGPPE PILAVVGEDA ELPCRLSPNA SAEHLELRWF RKKVSPAVLV HRDGREQEAE QMPEYRGRAT LVQDGIAKGR VALRIRGVRV SDDGEYTCFF REDGSYEEAL VHLKVAALGS DPHISMQVQE NGEICLECTS VGWYPEPQVQ WRTSKGEKFP STSESRNPDE EGLFTVAASV IIRDTSAKNV SCYIQNLLLG QEKKVEISIP ASSLPRVDHH HHHH
- Characteristics
- Recombinant Human Butyrophilin Subfamily 1 Member A1/BTN1A1 produced by transfected human cells is a secreted protein with sequence (Ala27-Arg242) of Human BTN1A1 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product BTN1A1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))
- Alternative Name
- btn1a1 (BTN1A1 Products)
- Synonyms
- BT Protein, BTN Protein, Btn Protein, BTN1A1 Protein, TVC Protein, butyrophilin subfamily 1 member A1 Protein, butyrophilin, subfamily 1, member A1 Protein, zgc:162154 Protein, BTN1A1 Protein, Btn1a1 Protein, btn1a1 Protein, zgc:162154 Protein
- Sub Type
- Fusionprotein
- Background
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Butyrophilin Subfamily 1 Member A1 (BTN1A1) is the major protein associated with fat droplets in the milk. It belongs the immunoglobulin superfamily. BTN1A1 acts as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. It is localized to the major histocompatibility complex (MHC) class I region of 6p. It may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. It is shown that BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Alternative Names: Butyrophilin Subfamily 1 Member A1, BT, BTN1A1, BTN - Molecular Weight
- 24.98 kDa
- UniProt
- Q13410
- Pathways
- Activated T Cell Proliferation
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