IGF2 Protein (AA 30-180, partial) (GST tag)
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- Target See all IGF2 Proteins
- IGF2 (Insulin-Like Growth Factor 2 (IGF2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-180, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IGF2 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS), ELISA
- Sequence
- ETLCGGELVD TLQFVCGDRG FYFSRPASRV SRRSRGIVEE CCFRSCDLAL LETYCATPAK SERDVSTPPT VLPDNFPRYP VGKFFQYDTW KQSTQRLRRG LPALLRARRG HVLAKELEAF REAKRHRPLI ALPTQDPAHG GAPPEMASNR K
- Characteristics
- The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. Ref.27 Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
- Purity
- 90 %
- Top Product
- Discover our top product IGF2 Protein
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- Comment
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Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS buffer, 20mM GSH
- Storage
- -20 °C
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Isolation of an insulin-like growth factor II cDNA with a unique 5' untranslated region from human placenta." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 6, pp. 1947-51, (1988) (PubMed).
: "Tissue-specific expression of insulin-like growth factor II mRNAs with distinct 5' untranslated regions." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 18, pp. 6330-4, (1987) (PubMed).
: "Organization of the human genes for insulin-like growth factors I and II." in: FEBS letters, Vol. 195, Issue 1-2, pp. 179-84, (1986) (PubMed).
: "Insulin-like growth factor II precursor gene organization in relation to insulin gene family." in: Nature, Vol. 310, Issue 5980, pp. 777-81, (1984) (PubMed).
: "Sequence of a cDNA clone encoding human preproinsulin-like growth factor II." in: Nature, Vol. 310, Issue 5980, pp. 775-7, (1984) (PubMed).
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Isolation of an insulin-like growth factor II cDNA with a unique 5' untranslated region from human placenta." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 6, pp. 1947-51, (1988) (PubMed).
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- Target
- IGF2 (Insulin-Like Growth Factor 2 (IGF2))
- Alternative Name
- Insulin-Like Growth Factor II (IGF2 Products)
- Synonyms
- C11orf43 Protein, IGF-II Protein, PP9974 Protein, LOC100136550 Protein, igf2 Protein, igf2b Protein, wu:fc26e03 Protein, zgc:91781 Protein, igf-2 Protein, insigf Protein, pp9974 Protein, AL033362 Protein, Igf-2 Protein, Igf-II Protein, M6pr Protein, Mpr Protein, Peg2 Protein, IGFII Protein, RNIGF2 Protein, IGF-II-B Protein, igf2-a Protein, igf2-b Protein, insulin like growth factor 2 Protein, insulin-like growth factor II Protein, insulin-like growth factor 2a Protein, insulin like growth factor 2 S homeolog Protein, insulin-like growth factor 2 Protein, insulin-like growth factor 2 (somatomedin A) Protein, insulin like growth factor 2 L homeolog Protein, IGF2 Protein, LOC100136550 Protein, igf2a Protein, igf2.S Protein, Igf2 Protein, igf2.L Protein
- Background
- Synonyms: IGF-II,Somatomedin-A
- Molecular Weight
- 44.5 kD
- UniProt
- P01344
- Pathways
- Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation
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