TIMP1 Protein (AA 24-207) (His tag)

Catalog No. ABIN1001180

Product Details

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Protein Type: Recombinant

Protein Characteristics: AA 24-207

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This TIMP1 protein is labelled with His tag.

Application: Western Blotting (WB), Control (Ct)

Purpose: Tissue Inhibitor of Metalloproteinase 1 (TIMP-1) (Western Blot Control)

Sequence: CTCVPPHPQT AFCNSDLVIR AKFVGTPEVN QTTLYQRYEI CTCVPPHPQT AFCNSDLVIR AKFVGTPEVN QTTLYQRYEI CTCVPPHPQT AFCNSDLVIR AKFVGTPEVN QTTLYQRYEI CTCVPPHPQT AFCNSDLVIR AKFVGTPEVN QTTLYQRYEI SRHLACLPRE PGLCTWQSLR SQIA

Characteristics: recombinant TIMP-1 comprises a 184 amino acid fragment (24-207) corresponding to the mature TIMP1 protein and is expressed in E. coli with an aminoterminal hexahistidine tag.

Purity: > 95 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in 1x Laemmli Buffer (25 mM Tris-HCl pH 6.8, 50 mM DTT, 1 % (w/v) SDS, 0.1 % (w/v) Bromophenol Blue, 2.5 % Glycerol).

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C

Target Details

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Alternative Name: Tissue Inhibitor of Metalloproteinase 1 (TIMP1 Products)

Synonyms: TIMP-1 Protein, TIMP1 Protein, DKFZp468A0912 Protein, CLGI Protein, EPA Protein, EPO Protein, HCI Protein, TIMP Protein, Timp Protein, Clgi Protein, TIMP metallopeptidase inhibitor 1 Protein, tissue inhibitor of metalloproteinase 1 Protein, TIMP1 Protein, Timp1 Protein

Background: TIMP-1 is an inducible glycoprotein, which is synthesized by many different cell types. TIMP-1 binds in a reversible fashion to matrix metalloproteinases, with regions in the Nterminal domain binding to the MMP substrate-binding site. TIMP-1 also functions as erthyroid-potentiating activity via translocation to the nucleus and also in inhibiting apoptosis in B-cells.,Soluble tumour necrosis factor receptor-1, Tumour necrosis factor receptor subfamily member 1A (TNFRSF1A), Tumour necrosis factor binding protein I (TNFBPI), Tumour necrosis factor receptor type I (TNFRI), Tumour necrosis factor-alpha receptor (TNFAR), CD120a antigen, p55, p55-R, p60, MGC19588.

Molecular Weight: 25.21 kDa

UniProt: P01033