Tissue factor Protein (AA 33-251) (His tag)

Catalog No. ABIN1001176

Product Details

Target: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Protein Type: Recombinant

Protein Characteristics: AA 33-251

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Tissue factor protein is labelled with His tag.

Application: Western Blotting (WB), Control (Ct)

Purpose: Tissue Factor (Western Blot Control)

Sequence: SGTTNTVAAY NLTWKSTNFK TILEWEPKPV NQVYTVQIST SGTTNTVAAY NLTWKSTNFK TILEWEPKPV NQVYTVQIST SGTTNTVAAY NLTWKSTNFK TILEWEPKPV NQVYTVQIST SGTTNTVAAY NLTWKSTNFK TILEWEPKPV NQVYTVQIST SGTTNTVAAY NLTWKSTNFK TILEWEPKPV NQVYTVQIST KSTDSPVECM GQEKGEFRE

Characteristics: recombinant Tissue Factor comprises a 219 amino acid fragment (33-251) corresponding to the extracellular domain of Tissue Factor protein and is expressed in E. coli with an amino-terminal hexahistidine tag.

Purity: > 95 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in 1x Laemmli Buffer (25 mM Tris-HCl pH 6.8, 50 mM DTT, 1 % (w/v) SDS, 0.1 % (w/v) Bromophenol Blue, 2.5 % Glycerol).

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C

Target Details

Target: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Alternative Name: Tissue Factor (F3 Products)

Synonyms: CD142 Protein, TF Protein, TFA Protein, PRO1557 Protein, PRO2086 Protein, TFQTL1 Protein, f3 Protein, AA409063 Protein, Cf-3 Protein, Cf3 Protein, tf Protein, zgc:112151 Protein, coagulation factor III, tissue factor Protein, transferrin Protein, coagulation factor IIIa Protein, coagulation factor III Protein, tissue factor Protein, coagulation factor IIIb Protein, coagulation factor III (thromboplastin, tissue factor) S homeolog Protein, F3 Protein, TF Protein, f3a Protein, tf Protein, f3b Protein, f3.S Protein

Background: Tissue factor is best known as the primary cellular initiator of blood coagulation. After vessel injury, the Tissue Factor : Factor VIIa complex activates the coagulation protease cascade, which leads to fibrin deposition and activation of platelets. In addition, aberrant Tissue Factor expression within the vasculature initiates life-threatening thrombosis in various diseases, such as sepsis, atherosclerosis, and cancer.,Coagulation Factor III, TF, Tissue Thromboplastin, CD142

Molecular Weight: 29.3 kDa

UniProt: P13726

Pathways: Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling