Soluble Tumor Necrosis Factor Receptor Type 2 (sTNF-R2) (AA 23-206) protein (His tag)
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- Target See all Soluble Tumor Necrosis Factor Receptor Type 2 (sTNF-R2) Proteins
- Soluble Tumor Necrosis Factor Receptor Type 2 (sTNF-R2)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-206
- Origin
- Human
- Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- His tag
- Application
- Western Blotting (WB), ELISA
- Purpose
- Soluble Tumour Necrosis Factor Receptor 2 (STNF-R2)
- Sequence
- LPAQVAFTPY APEPGSTCRL REYYDQTAQM CCSKCSPGQH LPAQVAFTPY APEPGSTCRL REYYDQTAQM CCSKCSPGQH LPAQVAFTPY APEPGSTCRL REYYDQTAQM CCSKCSPGQH LPAQVAFTPY APEPGSTCRL REYYDQTAQM CCSKCSPGQH QICNVVAIPG NASMDAVCTS TSPT
- Characteristics
- recombinant sTNFR-II comprises a 184 amino acid fragment (23-206) corresponding to the mature sTNFR-II protein and is expressed in E. coli with an aminoterminal hexahistidine tag.
- Purity
- > 95 %
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 20 mM Tris HCl pH 8, 5 mM EDTA, 50 % Glycerol
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C
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- Target
- Soluble Tumor Necrosis Factor Receptor Type 2 (sTNF-R2)
- Abstract
- sTNF-R2 Products
- Synonyms
- CD120b Protein, TBPII Protein, TNF-R-II Protein, TNF-R75 Protein, TNFBR Protein, TNFR1B Protein, TNFR2 Protein, TNFR80 Protein, p75 Protein, p75TNFR Protein, TNF-R2 Protein, TNF-alphaR2 Protein, TNFRII Protein, TNFalpha-R2 Protein, Tnfr-1 Protein, Tnfr2 Protein, TNF receptor superfamily member 1B Protein, tumor necrosis factor receptor superfamily, member 1b Protein, TNFRSF1B Protein, Tnfrsf1b Protein
- Background
- Two types of soluble TNF receptors (sTNFR-I and sTNFRII) have been identified, which act to neutralize the biological activities of TNF alpha and TNF beta. Levels of these soluble receptors appear to arise as a result of shedding of the extracellular domains of the membrane bound receptors. Elevated levels of soluble TNF receptors have been found in the amniotic fluid of pregnant women.,Tumour necrosis factor receptor 2, Tumour receptor beta receptor, Tumour necrosis factor binding protein 2, Tumour necrosis factor receptor superfamily member 1B, Tumour necrosis factor receptor type II, p80 TNF alpha receptor, Etanercept, CD120b, p75, TBPII, TNFRII, TNFR75, TNFBR, TNFR2, TNFR80.
- Molecular Weight
- 24.45 kDa
- UniProt
- P20333
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