Soluble Tumor Necrosis Factor Receptor Type 1 (sTNF-R1) (AA 41-201) protein (His tag)
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- Target See all Soluble Tumor Necrosis Factor Receptor Type 1 (sTNF-R1) Proteins
- Soluble Tumor Necrosis Factor Receptor Type 1 (sTNF-R1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 41-201
- Origin
- Human
- Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- His tag
- Application
- Western Blotting (WB), ELISA
- Purpose
- Soluble Tumour Necrosis Factor Receptor 1 (STNF-R1)
- Sequence
- DSVCPQGKYI HPQNNSICCT KCHKGTYLYN DCPGPGQDTD DSVCPQGKYI HPQNNSICCT KCHKGTYLYN DCPGPGQDTD DSVCPQGKYI HPQNNSICCT KCHKGTYLYN DCPGPGQDTD DSVCPQGKYI HPQNNSICCT KCHKGTYLYN DCPGPGQDTD N
- Characteristics
- recombinant sTNFR-I comprises a 161 amino acid fragment (41-201) corresponding to the mature sTNFR-I protein and is expressed in E. coli with an aminoterminal hexahistidine tag.
- Purity
- > 95 %
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 20 mM Tris HCl pH 8, 1 mM EDTA, 50 % Glycerol
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C
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- Target
- Soluble Tumor Necrosis Factor Receptor Type 1 (sTNF-R1)
- Abstract
- sTNF-R1 Products
- Synonyms
- CD120a Protein, FPF Protein, MS5 Protein, TBP1 Protein, TNF-R Protein, TNF-R-I Protein, TNF-R55 Protein, TNFAR Protein, TNFR1 Protein, TNFR1-d2 Protein, TNFR55 Protein, TNFR60 Protein, p55 Protein, p55-R Protein, p60 Protein, TNF receptor superfamily member 1A Protein, TNFRSF1A Protein
- Background
- Two types of soluble TNF receptors (sTNFR-I and sTNFRII) have been identified, which act to neutralize the biological activities of TNF alpha and TNF beta. Levels of these soluble receptors appear to arise as a result of shedding of the extracellular domains of the membrane bound receptors. Elevated levels of soluble TNF receptors have been found in the amniotic fluid of pregnant women.,Soluble tumour necrosis factor receptor-1, Tumour necrosis factor receptor subfamily member 1A (TNFRSF1A), Tumour necrosis factor binding protein I (TNFBPI), Tumour necrosis factor receptor type I (TNFRI), Tumour necrosis factor-alpha receptor (TNFAR), CD120a antigen, p55, p55-R, p60, MGC19588.
- Molecular Weight
- 22.68 kDa
- UniProt
- P19438
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