PPARG Protein (AA 29-505) (His tag)
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- Target See all PPARG Proteins
- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 29-505
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PPARG protein is labelled with His tag.
- Application
- Western Blotting (WB), Control (Ct)
- Purpose
- Peroxisom Proliferator-Acivated Receptor Gamma (PPAR-g) (Western Blot Control)
- Sequence
- MTMVDTEMPF WPTNFGISSV DLSVMEDHSH SFDIKPFTTV MTMVDTEMPF WPTNFGISSV DLSVMEDHSH SFDIKPFTTV MTMVDTEMPF WPTNFGISSV DLSVMEDHSH SFDIKPFTTV MTMVDTEMPF WPTNFGISSV DLSVMEDHSH SFDIKPFTTV MTMVDTEMPF WPTNFGISSV DLSVMEDHSH SFDIKPFTTV MTMVDTEMPF WPTNFGISSV DLSVMEDHSH SFDIKPFTTV MTMVDTEMPF WPTNFGISSV DLSVMEDHSH SFDIKPFTTV MTMVDTEMPF WPTNFGISSV DLSVMEDHSH SFDIKPFTTV MTMVDTEMPF WPTNFGISSV DLSVMEDHSH SFDIKPFTTV MTMVDTEMPF WPTNFGISSV DLSVMEDHSH SFDIKPFTTV MTMVDTEMPF WPTNFGISSV DLSVMEDHSH SFDIKPFTTV DLRQIVTEHV QLLQVIKKTE TDMSLHPLLQ EIYKDLYZ
- Characteristics
- recombinant PPAR? comprises a 477 amino acid fragment (29-505) corresponding to the mature PPAR? protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
- Purity
- > 95 %
- Top Product
- Discover our top product PPARG Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in 1x Laemmli Buffer (25 mM Tris-HCl pH 6.8, 50 mM DTT, 1 % (w/v) SDS, 0.1 % (w/v) Bromophenol Blue, 2.5 % Glycerol).
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C
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- Target
- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
- Abstract
- PPARG Products
- Synonyms
- PPAR gamma Protein, PPARg2 Protein, PPARG Protein, Nr1c3 Protein, PPAR-gamma Protein, PPAR-gamma2 Protein, PPARgamma Protein, PPARgamma2 Protein, NR1C3 Protein, CIMT1 Protein, GLM1 Protein, PPARG1 Protein, PPARG2 Protein, xPPAR-gamma Protein, PPAR-GAMMA Protein, PPARGAMMA Protein, peroxisome proliferator-activated receptor gamma Protein, peroxisome proliferator activated receptor gamma Protein, peroxisome proliferator activated receptor gamma L homeolog Protein, PPARG Protein, Pparg Protein, pparg.L Protein
- Background
- This nuclear receptor functions as a transcription factor and plays an important role in controlling differentiation and fatty acid metabolism. Activation of this receptor appears to be vital in modulating the expression of metabolic control proteins and consequently controlling fatty acid metabolism in cardiac muscle. This marker may be a useful drug target for therapeutic intervention in cardiac disease. PPARg is also involved in the pathogenesis of important metabolic disorders such as obesity and non-insulin-dependent diabetes (NIDDM).,Peroxisome Proliferator-Activated Receptor, ?-isotype
- Molecular Weight
- 59.18 kDa
- UniProt
- P37231
- Pathways
- MAPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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