IL-6 Receptor Protein (AA 20-357) (His tag)
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- Target See all IL-6 Receptor (IL6R) Proteins
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-357
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IL-6 Receptor protein is labelled with His tag.
- Application
- Western Blotting (WB), Control (Ct)
- Purpose
- Interleukin-6 Soluable Receptor (IL-6SR) (Western Blot Control)
- Sequence
- LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH DDNILFRDSA NATSLPVQ
- Characteristics
- recombinant IL6-sR comprises a 338 amino acid fragment (20-357) corresponding to the mature IL6- sR protein and is expressed in E. coli with an aminoterminal hexahistidine tag.
- Purity
- > 95 %
- Top Product
- Discover our top product IL6R Protein
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Interleukin 6 Receptor (IL6R) (AA 20-365) protein (His tag)
IL6R Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Interleukin 6 Receptor (IL6R) (AA 20-365) protein (Fc Tag)IL6R Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 6 Receptor (IL6R) (AA 229-468) protein (His-IF2DI Tag)IL6R Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 6 Receptor (IL6R) (AA 21-120) protein (GST tag)IL6R Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 6 Receptor (IL6R) (AA 1-468) protein (GST tag)IL6R Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in 1x Laemmli Buffer (25 mM Tris-HCl pH 6.8, 50 mM DTT, 1 % (w/v) SDS, 0.1 % (w/v) Bromophenol Blue, 2.5 % Glycerol).
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C
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- Target
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- Alternative Name
- Interleukin-6 Soluable Receptor (IL6R Products)
- Synonyms
- IL6R Protein, il-6ra Protein, CD126 Protein, IL-6R-1 Protein, IL-6RA Protein, IL6Q Protein, IL6RA Protein, IL6RQ Protein, gp80 Protein, IL6R1 Protein, Il6ra Protein, IL-6Ralpha Protein, IL-6R Protein, Il6r Protein, interleukin 6 receptor Protein, interleukin 6 receptor, alpha Protein, IL6R Protein, il6r Protein, Il6r Protein, Il6ra Protein
- Background
- The IL-6 receptor complex is composed of two membrane glycoproteins: the low affinity receptor and the signaltransducing component. The soluble form of IL6R is found in the urine of healthy adult humans and the serum of HIV positive individuals, as well as in the cell culture supernatants of stimulated PBMC's. This soluble form of IL6R results from either proteolytic cleavage from the membrane, or an isoform derived splice variant.,IL6R-alpha, IL-6R 1, CD126 antigen, IL6RA, interleukin 6 receptor, interleukin 6 receptor alpha subunit, Interleukin6 receptor alpha chain precursor.
- Molecular Weight
- 42.45 kDa
- UniProt
- P08887
- Pathways
- JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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