Haptoglobin beta Chain (HP) (AA 162-406) protein (His tag)
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- Target See all Haptoglobin beta Chain (HP) Proteins
- Haptoglobin beta Chain (HP)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 162-406
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- His tag
- Application
- Western Blotting (WB), ELISA
- Purpose
- Haptoglobin B-Chain
- Sequence
- ILGGHLDAKG SFPWQAKMVS HHNLTTGATL INEQWLLTTA ILGGHLDAKG SFPWQAKMVS HHNLTTGATL INEQWLLTTA ILGGHLDAKG SFPWQAKMVS HHNLTTGATL INEQWLLTTA ILGGHLDAKG SFPWQAKMVS HHNLTTGATL INEQWLLTTA ILGGHLDAKG SFPWQAKMVS HHNLTTGATL INEQWLLTTA ILGGHLDAKG SFPWQAKMVS HHNLTTGATL INEQWLLTTA TIAEN
- Characteristics
- recombinant Haptoglobin β-chain comprises a 245 amino acid fragment (162-406) corresponding to the mature haptoglobin β-chain and is expressed in E. coli with an amino-terminal hexahistidine tag.
- Purity
- > 95 %
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 20 mM Tris-HCl pH 8.0, 50 % Glycerol
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C
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- Target
- Haptoglobin beta Chain (HP)
- Abstract
- HP Products
- Synonyms
- HP-1 Protein, BP Protein, HP2ALPHA2 Protein, HPA1S Protein, haptoglobin Protein, HP Protein, Hp Protein
- Background
- Haptoglobin is a glycoprotein secreted in the blood plasma that binds free haemoglobin thereby inhibiting its oxidative activity and preventing iron loss following haemolysis. Haptoglobin also regulates the activity of many cell types of the immune system and is an extracellular chaperone. Haptoglobin is produced mostly by hepatocytes but also by other tissues: e.g. skin, lung and kidney. Haptoglobin is a tetramer of two α- and two β-chains, connected by disulfide bridges. The chains originate from a common precursor protein, which is proteolytically cleaved during protein synthesis.,Hp, Bp
- Molecular Weight
- 31.76 kDa
- UniProt
- P00738
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