GSTO1 Protein (AA 1-241) (His tag)
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- Target See all GSTO1 Proteins
- GSTO1 (Glutathione S-Transferase omega 1 (GSTO1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-241
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GSTO1 protein is labelled with His tag.
- Application
- Western Blotting (WB), Control (Ct)
- Purpose
- Glutathione S-Transferase Omega 1 (GST-01) (Western Blot Control)
- Sequence
- MSGESARSLG KGSAPPGPVP EGSIRIYSMR FCPFAERTRL MSGESARSLG KGSAPPGPVP EGSIRIYSMR FCPFAERTRL MSGESARSLG KGSAPPGPVP EGSIRIYSMR FCPFAERTRL MSGESARSLG KGSAPPGPVP EGSIRIYSMR FCPFAERTRL MSGESARSLG KGSAPPGPVP EGSIRIYSMR FCPFAERTRL MSGESARSLG KGSAPPGPVP EGSIRIYSMR FCPFAERTRL L
- Characteristics
- recombinant GSTO1 140D comprises a 241 amino acid fragment (1-241) corresponding to the GSTO1 140D mutant mature protein, which is expressed in E. coli with an amino-terminal hexahistidine tag.
- Purity
- > 95 %
- Top Product
- Discover our top product GSTO1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in 1x Laemmli Buffer (25 mM Tris-HCl pH 6.8, 50 mM DTT, 1 % (w/v) SDS, 0.1 % (w/v) Bromophenol Blue, 2.5 % Glycerol).
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C
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- Target
- GSTO1 (Glutathione S-Transferase omega 1 (GSTO1))
- Alternative Name
- Glutathione S-Transferase Omega 1 (GSTO1 Products)
- Synonyms
- SPG-R Protein, GSTO 1-1 Protein, GSTTLp28 Protein, P28 Protein, AA407097 Protein, AI194287 Protein, AU018802 Protein, GSTX Protein, p28 Protein, GSTO1 Protein, glutathione S-transferase omega 1 Protein, glutathione S-transferase omega 1 S homeolog Protein, GSTO1 Protein, gsto1.S Protein, GSTo1 Protein, Gsto1 Protein
- Background
- GSTO1 is a member of the theta class glutathione Stransferase-like (GSTTL) protein family. GSTO1 is expressed in a wide range of human tissues and exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities and also catalyzes the reduction of monomethylarsonate, an intermediate in the pathway of arsenic biotransformation. GSTO1 protects from oxidative stress, a risk factor for Alzheimer disease, vascular dementia and stroke. Several polymorphisms in the coding regions of the human GSTO1 have been identified. A polymorphism causing an alanine-toaspartate (A140D) substitution in amino acid 140 produces a variant with lowered enzyme activities in the arsenic biotransformation.,GSTTLp28, P28, glutathione S-transferase omega 1-1, glutathione transferase omega, glutathione transferase omega 1, glutathione-S-transferase like, Monomethyl Arsenous Reductase.
- Molecular Weight
- 32.11 kDa
- UniProt
- P78417
- Pathways
- Myometrial Relaxation and Contraction, Negative Regulation of Transporter Activity
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