ADAM10 Protein (AA 214-672) (His tag)

Catalog No. ABIN1000828

Product Details

Target: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Protein Type: Recombinant

Protein Characteristics: AA 214-672

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This ADAM10 protein is labelled with His tag.

Application: Western Blotting (WB), ELISA

Purpose: ADAM 10

Sequence: TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI LARLKKAIFS PELYENIAE

Characteristics: recombinant ADAM 10 comprises a 459 amino acid fragment (214-672) corresponding to the ADAM 10 extracellular domain minus the signal peptide and prosequence and is expressed in E. coli with an aminoterminal hexahistidine tag.

Purity: > 95 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 20 mM Tris-HCl pH 8.0, 5 mM EDTA, 50 % Glycerol

Storage: -20 °C

Storage Comment: Store at -20 °C

Target Details

Target: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Alternative Name: ADAM 10 (ADAM10 Products)

Synonyms: ADAM10 Protein, Adam10 Protein, adam10 Protein, wu:fc03d12 Protein, ad10 Protein, cd156c Protein, kuz Protein, kuzbanian Protein, madm Protein, xadam10 Protein, ADAM-10 Protein, ADAM 10 Protein, AD10 Protein, CD156c Protein, HsT18717 Protein, MADM Protein, 1700031C13Rik Protein, LOC100219653 Protein, zgc:64203 Protein, ADAM metallopeptidase domain 10 Protein, ADAM metallopeptidase domain 10a Protein, ADAM metallopeptidase domain 10 S homeolog Protein, a disintegrin and metallopeptidase domain 10 Protein, ADAM metallopeptidase domain 10b Protein, ADAM10 Protein, Adam10 Protein, adam10a Protein, adam10.S Protein, adam10b Protein

Background: ADAM 10 is a member of the ADAM family of membraneanchored cell surface proteins, which contain both a disintegrin and a metalloprotease domain. ADAM 10 is expressed in a wide variety of tissues and resides on both the cell surface and within the cytoplasm. ADAM10 has been implicated in proteolytic release of a number of cell surface proteins in particular TNF alpha,AD10, KUZ, EC 3.4.24.81, A desintegrin and metalloprotease domain 10, mammalian disintegrinmetalloprotease, Kuzbanian protein homolog, CDw156c antigen

Molecular Weight: 55.09 kDa

UniProt: O14672

Pathways: Notch Signaling, EGFR Signaling Pathway