ADAM12 S Isoform Protein (AA 208-738) (His tag)
ADAM12 S Isoform
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, ELISA
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- Target See all ADAM12 S Isoform products
- ADAM12 S Isoform (A Disintegrin and Metalloproteinase Domain 12 S (ADAM12 S Isoform))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 208-738
- Origin
- Human
- Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ADAM12 S Isoform protein is labelled with His tag.
- Application
- Western Blotting (WB), ELISA
- Purpose
- ADAM 12S
- Sequence
- ETLKATKYVE LVIVADNREF QRQGKDLEKV KQRLIEIANH ETLKATKYVE LVIVADNREF QRQGKDLEKV KQRLIEIANH ETLKATKYVE LVIVADNREF QRQGKDLEKV KQRLIEIANH ETLKATKYVE LVIVADNREF QRQGKDLEKV KQRLIEIANH ETLKATKYVE LVIVADNREF QRQGKDLEKV KQRLIEIANH ETLKATKYVE LVIVADNREF QRQGKDLEKV KQRLIEIANH ETLKATKYVE LVIVADNREF QRQGKDLEKV KQRLIEIANH ETLKATKYVE LVIVADNREF QRQGKDLEKV KQRLIEIANH ETLKATKYVE LVIVADNREF QRQGKDLEKV KQRLIEIANH ETLKATKYVE LVIVADNREF QRQGKDLEKV KQRLIEIANH ETLKATKYVE LVIVADNREF QRQGKDLEKV KQRLIEIANH ETLKATKYVE LVIVADNREF QRQGKDLEKV KQRLIEIANH ETLKATKYVE LVIVADNREF QRQGKDLEKV KQRLIEIANH EHASTASLTL I
- Characteristics
- recombinant ADAM12S comprises a 531 amino acid fragment (208-738) corresponding to the mature ADAM 12S protein isoform and is expressed in E. coli with an amino-terminal hexahistidine tag.
- Purity
- > 95 %
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-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 25 mM Sodium Acetate pH 4.8, 50 % Glycerol
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C
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- Target
- ADAM12 S Isoform (A Disintegrin and Metalloproteinase Domain 12 S (ADAM12 S Isoform))
- Abstract
- ADAM12 S Isoform Products
- Background
- ADAM proteins are a family of membrane-anchored cell surface protein containing both a disintegrin and a metalloprotease domain. Their exact functions have not been fully characterised however, they are thought to mediate a number of cellular processes including differentiation, cell fusion, cell-cell interactions and shedding of plasma membrane bound growth factor precursors. Two forms of ADAM12 have been described: ADAM12S and ADAM12L (short and long forms). The short form (ADAM12S) is a soluble form, which lacks the transmembrane and cytoplasmic domains. ADAM12S expression is thought to be limited to the placenta, embryo and foetus although levels have been detected in some tumour cell lines,A Disintegrin and Metalloprotease Domain 12 S isoform, ADAM12 precursor (EC 3.4.24), Meltrin alpha
- Molecular Weight
- 62.16 kDa
- UniProt
- O43184
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