PRSS8 Products
(Protease, serine, 8 (PRSS8))
Categories
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine. [provided by RefSeq, Jul 2008].
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Featured PRSS8 Categories
PRSS8 Antibodies
High quality antibodies with extensive validation data.
PRSS8 ELISA Kits
Reliable ELISA kits for a wide range of species.
PRSS8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PRSS8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7436249
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (7)
Cat. No.
ABIN519337
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
- (3)
Cat. No.
ABIN761891
Quantity
100 μL
Datasheet
Datasheet
Recommended PRSS8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958891
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6974928
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969690
Quantity
96 tests
Datasheet
Datasheet
Recommended PRSS8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1316486
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316488
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7197548
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our PRSS8 products
: "Albuminuria is associated with an increased prostasin in urine while aldosterone has no direct effect on urine and kidney tissue abundance of prostasin." in: Pflügers Archiv : European journal of physiology, Vol. 469, Issue 5-6, pp. 655-667, (2018) (PubMed).: "PRSS8 is Downregulated and Suppresses Tumour Growth and Metastases in Hepatocellular Carcinoma." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 40, Issue 3-4, pp. 757-769, (2016) (PubMed).
: "Diabetic nephropathy is associated with increased urine excretion of proteases plasmin, prostasin and urokinase and activation of amiloride-sensitive current in collecting duct cells." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, (2015) (PubMed).
: "Increased expression of prostasin contributes to early-onset severe preeclampsia through inhibiting trophoblast invasion." in: Journal of perinatology : official journal of the California Perinatal Association, Vol. 35, Issue 1, pp. 16-22, (2014) (PubMed).
: "Gene expression and pathway analysis of ovarian cancer cells selected for resistance to cisplatin, paclitaxel, or doxorubicin." in: Journal of ovarian research, Vol. 4, Issue 1, pp. 21, (2012) (PubMed).
: "Prostasin-dependent activation of epithelial Na+ channels by low plasmin concentrations." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 297, Issue 6, pp. R1733-41, (2009) (PubMed).
: "Down-regulation of prostasin serine protease: a potential invasion suppressor in prostate cancer." in: The Prostate, Vol. 48, Issue 2, pp. 93-103, (2001) (PubMed).
: "Prostasin is a glycosylphosphatidylinositol-anchored active serine protease." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21434-42, (2001) (PubMed).
: "Molecular cloning, tissue-specific expression, and cellular localization of human prostasin mRNA." in: The Journal of biological chemistry, Vol. 270, Issue 22, pp. 13483-9, (1995) (PubMed).
: "Prostasin is a novel human serine proteinase from seminal fluid. Purification, tissue distribution, and localization in prostate gland." in: The Journal of biological chemistry, Vol. 269, Issue 29, pp. 18843-8, (1994) (PubMed).
Synonyms and alternative names related to PRSS8
protease, serine 8 (PRSS8), protease, serine, 8 (Prss8), protease, serine 8 (prostasin) (Prss8), protease, serine, 8 (PRSS8), 2410039E18Rik, AI313909, C79772, CAP1, fr, mCAP1, PROSTASIN, prostasinProtein level used designations for PRSS8
- channel-activating protease 1
- prostasin
- serine protease 8
- channel activating protease 1
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