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PRPF4 Products

(PRP4 Pre-mRNA Processing Factor 4 Homolog (PRPF4))

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The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

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Featured PRPF4 Categories

PRPF4 Antibodies

High quality antibodies with extensive validation data.

PRPF4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PRPF4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
  • (3)
Cat. No. ABIN522584
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7174174
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7164157
Quantity 100 μg
Datasheet Datasheet

Recommended PRPF4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6233669
Quantity 96 tests
Datasheet Datasheet

Recommended PRPF4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316393
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3129500
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3086476
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PRPF4 products

Adler, McCleland, Yee, Yaylaoglu, Hussain, Cosino, Quinones, Modrusan, Seshagiri, Torres, Chopra, Haley, Zhang, Blackwood, Singh, Junttila, Stephan, Liu, Pau, Fearon, Jiang, Firestein: "An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth." in: Genes & development, Vol. 28, Issue 10, pp. 1068-84, (2014) (PubMed).

Shehzad, Park, Lee, Lee: "Curcumin induces radiosensitivity of in vitro and in vivo cancer models by modulating pre-mRNA processing factor 4 (Prp4)." in: Chemico-biological interactions, Vol. 206, Issue 2, pp. 394-402, (2013) (PubMed).

Tanackovic, Ransijn, Thibault, Abou Elela, Klinck, Berson, Chabot, Rivolta: "PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa." in: Human molecular genetics, Vol. 20, Issue 11, pp. 2116-30, (2011) (PubMed).

Synonyms and alternative names related to PRPF4

pre-mRNA processing factor 4 (Prpf4), PRP4 pre-mRNA processing factor 4 homolog (yeast) (prpf4), pre-mRNA processing factor 4 L homeolog (prpf4.L), pre-mRNA processing factor 4 (PRPF4), U4/U6 small nuclear ribonucleoprotein Prp4 (LOC409689), U4/U6 small nuclear ribonucleoprotein (prpf4), 1600015H11Rik, AI874830, AW047464, bN189G18.1, DDBDRAFT_0187564, DDBDRAFT_0233058, DDB_0187564, DDB_0233058, GB19235, HPRP4, HPRP4P, mg:ab03a02, PRP4, Prp4p, SNRNP60, zgc:65943

Protein level used designations for PRPF4

  • U4/U6 small nuclear ribonucleoprotein Prp4
  • PRP4 pre-mRNA processing factor 4 homolog (yeast)
  • WD40 repeat-containing protein
  • pre-mRNA processing factor 4
  • U4/U6 small nuclear ribonucleoprotein Prp4-like
  • PRP4 homolog
  • PRP4/STK/WD splicing factor
  • U4/U6 snRNP 60 kDa protein
  • WD splicing factor Prp4
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