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Proteolipid Protein 1 Products

(Proteolipid Protein 1 (PLP1))

Categories

This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene. [provided by RefSeq, Jul 2008].

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Featured Proteolipid Protein 1 Categories

Proteolipid Protein 1 Antibodies

High quality antibodies with extensive validation data.

Proteolipid Protein 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Proteolipid Protein 1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Proteolipid Protein 1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7269724
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (4)
Cat. No. ABIN950033
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7160433
Quantity 100 μg
Datasheet Datasheet

Recommended Proteolipid Protein 1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958973
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969765
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958974
Quantity 96 tests
Datasheet Datasheet

Recommended Proteolipid Protein 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1315455
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (2)
Cat. No. ABIN3098888
Quantity 0.25 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124694
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Proteolipid Protein 1 products

Sinclair, Kumar, Darreh-Shori, Love et al.: "Visual hallucinations in Alzheimer's disease do not seem to be associated with chronic hypoperfusion of to visual processing areas V2 and V3 but may be associated with reduced cholinergic input to ..." in: Alzheimer's research & therapy, Vol. 11, Issue 1, pp. 80, (2020) (PubMed).

Sghaier, Nury, Leoni, Caccia, Pais De Barros, Cherif, Vejux, Moreau, Limem, Samadi, Mackrill, Masmoudi, Lizard, Zarrouk: "Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol." in: The Journal of steroid biochemistry and molecular biology, Vol. 194, pp. 105432, (2019) (PubMed).

Ziemka-Nalecz, Janowska, Strojek, Jaworska, Zalewska, Frontczak-Baniewicz, Sypecka: "Impact of neonatal hypoxia-ischaemia on oligodendrocyte survival, maturation and myelinating potential." in: Journal of cellular and molecular medicine, Vol. 22, Issue 1, pp. 207-222, (2018) (PubMed).

Chierto, Simon, Castoldi, Meffre, Cristinziano, Sapone, Carrete, Borderie, Etienne, Rannou, Morrison, Massaad, Jafarian-Tehrani: "Mechanical Stretch of High Magnitude Provokes Axonal Injury, Elongation of Paranodal Junctions, and Signaling Alterations in Oligodendrocytes." in: Molecular neurobiology, (2018) (PubMed).

Miners, Palmer, Love: "Pathophysiology of Hypoperfusion of the Precuneus in Early Alzheimer's Disease." in: Brain pathology (Zurich, Switzerland), (2015) (PubMed).

Li, Tsuneki, Krauthammer, Couture, Schwartz, Madri: "Modulation of Sox10, HIF-1?, Survivin, and YAP by Minocycline in the Treatment of Neurodevelopmental Handicaps following Hypoxic Insult." in: The American journal of pathology, (2015) (PubMed).

Cachón-González, Wang, Ziegler, Cheng, Cox: "Reversibility of neuropathology in Tay-Sachs-related diseases." in: Human molecular genetics, Vol. 23, Issue 3, pp. 730-48, (2014) (PubMed).

Hinson, Romero, Popescu, Lucchinetti, Fryer, Wolburg, Fallier-Becker, Noell, Lennon: "Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 4, pp. 1245-50, (2012) (PubMed).

van Horssen, Singh, van der Pol, Kipp, Lim, Peferoen, Gerritsen, Kooi, Witte, Geurts, de Vries, Peferoen-Baert, van den Elsen, van der Valk, Amor: "Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation." in: Journal of neuroinflammation, Vol. 9, pp. 156, (2012) (PubMed).

Horiuchi, Maezawa, Itoh, Wakayama, Jin, Itoh, Decarli: "Amyloid β1-42 oligomer inhibits myelin sheet formation in vitro." in: Neurobiology of aging, Vol. 33, Issue 3, pp. 499-509, (2012) (PubMed).

Synonyms and alternative names related to Proteolipid Protein 1

proteolipid protein 1 (PLP1), proteolipid protein 1 (Plp1), proteolipid protein 1 (plp1), proteolipid protein (myelin) 1 (Plp1), myelin proteolipid protein (Tsp_11640), myelin proteolipid protein (plp), proteolipid protein 1 L homeolog (plp1.L), proteolipid protein 1a (plp1a), proteolipid protein 1 S homeolog (plp1.S), DKFZp459O081, DKFZp459O113, DM20, DMalpha2c, GPM6C, HLD1, hld1, jimpy, jp, MMPL, mmpl, msd, PLP, Plp, plp, PLP-B, PLP/DM20, PLP1, plp1, plp1-a, plp1-b, plp1a, plp1b, PMD, pmd, rsh, SPG2, spg2, wu:fc27f01, wu:fj36d03, wu:fj42d08, zgc:110499

Protein level used designations for Proteolipid Protein 1

  • lipophilin
  • major myelin proteolipid protein
  • myelin proteolipid protein
  • Proteolipid protein (Pelizaeus-Merzbacher disease spastic paraplegia 2 uncomplicated)
  • Proteolipid protein (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated)
  • proteolipid protein (myelin) 1
  • proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated)
  • proteolipid protein, lipophilin
  • proteolipid protein 1
  • myelin synthesis deficiency
  • rump shaker
  • PLP
  • PLP-A
  • lipophilin-A
  • myelin proteolipid protein (PLP)
  • myelin proteolipid protein A
  • proteolipid protein 1 a
  • DMalpha1
  • etID60288.14
  • Lipophilin-B
  • myelin proteolipid protein B
  • proteolipid protein 1 b
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