Protein tyrosine Phosphatase, Receptor Type, J Products
(Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Protein tyrosine Phosphatase, Receptor Type, J Antibodies
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Protein tyrosine Phosphatase, Receptor Type, J Proteins
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Recommended Protein tyrosine Phosphatase, Receptor Type, J Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7441778
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN7440614
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (4)
Cat. No.
ABIN7193256
Quantity
100 μL
Datasheet
Datasheet
Recommended Protein tyrosine Phosphatase, Receptor Type, J ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969755
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958961
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4882596
Quantity
96 tests
Datasheet
Datasheet
Recommended Protein tyrosine Phosphatase, Receptor Type, J Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124686
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316873
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7412191
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Protein tyrosine Phosphatase, Receptor Type, J products
: "A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis." in: Oncotarget, Vol. 8, Issue 6, pp. 10091-10102, (2018) (PubMed).: "The protein tyrosine phosphatase DEP-1/PTPRJ promotes breast cancer cell invasion and metastasis." in: Oncogene, Vol. 34, Issue 44, pp. 5536-47, (2015) (PubMed).
: "Phosphorylation of DEP-1/PTPRJ on threonine 1318 regulates Src activation and endothelial cell permeability induced by vascular endothelial growth factor." in: Cellular signalling, Vol. 26, Issue 6, pp. 1283-93, (2014) (PubMed).
: "Polymorphisms of protein tyrosine phosphatase CD148 influence FcγRIIA-dependent platelet activation and the risk of heparin-induced thrombocytopenia." in: Blood, Vol. 120, Issue 6, pp. 1309-16, (2012) (PubMed).
: "Systematic validation of specific phenotypic markers for in vitro polarized human macrophages." in: Journal of immunological methods, Vol. 375, Issue 1-2, pp. 196-206, (2012) (PubMed).
: "Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148." in: The Journal of biological chemistry, Vol. 286, Issue 25, pp. 22101-12, (2011) (PubMed).
: "Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry." in: Immunology letters, Vol. 134, Issue 2, pp. 113-21, (2010) (PubMed).
: "Analysis of HLDA9 mAbs on plasmacytoid dendritic cells." in: Immunology letters, Vol. 134, Issue 2, pp. 167-73, (2010) (PubMed).
: "Tumor suppressor density-enhanced phosphatase-1 (DEP-1) inhibits the RAS pathway by direct dephosphorylation of ERK1/2 kinases." in: The Journal of biological chemistry, Vol. 284, Issue 33, pp. 22048-58, (2009) (PubMed).
: "CD148 and CD27 are expressed in B cell lymphomas derived from both memory and naïve B cells." in: Leukemia & lymphoma, Vol. 43, Issue 9, pp. 1855-8, (2003) (PubMed).
Synonyms and alternative names related to Protein tyrosine Phosphatase, Receptor Type, J
acid phosphatase 1 (ACP1), protein tyrosine phosphatase, receptor type J (PTPRJ), protein tyrosine phosphatase, receptor type, J (Ptprj), protein tyrosine phosphatase, receptor type, J (PTPRJ), protein tyrosine phosphatase, receptor type, J (EUBREC_2762), AI450271, BET, Byp, CD148, DEP-1, DEP1, HAAP, HPTPeta, Ptpb2, PTPbeta2, PTPRJ, R-PTP-ETA, RPTPJ, Scc-1, SCC1, Scc1Protein level used designations for Protein tyrosine Phosphatase, Receptor Type, J
- LMW-PTP
- LMW-PTPase
- acid phosphatase of erythrocyte
- adipocyte acid phosphatase
- cytoplasmic phosphotyrosyl protein phosphatase
- low molecular weight cytosolic acid phosphatase
- low molecular weight phosphotyrosine protein phosphatase
- protein tyrosine phosphatase
- red cell acid phosphatase 1
- CD148 antigen
- DEP-1
- HPTP eta
- R-PTP-J
- density-enhanced phosphatase 1
- human density enhanced phosphatase-1
- protein tyrosine phosphatase, receptor type, J polypeptide
- protein-tyrosine phosphatase eta
- protein-tyrosine phosphatase receptor type J
- receptor-type tyrosine-protein phosphatase eta
- susceptibility to colon cancer 1, mouse, homolog of
- HPTP beta-like tyrosine phosphatase
- R-PTP-eta
- colon tumor susceptibility 1
- susceptibility to colon cancer 1
- density enhanced phosphatase-1
- supporting-cell antigen
- protein tyrosine phosphatase, receptor type, J
- receptor-type tyrosine-protein phosphatase eta-like
Did you look for something else?
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- Protein Phosphatase 4, Regulatory Subunit 2
- Protein Phosphatase 2, Regulatory Subunit B', epsilon Isoform
- Protein Phosphatase 2, Regulatory Subunit B', delta
- Protein Phosphatase 1, Regulatory Subunit 3C
- Protein Phosphatase 1, Regulatory Subunit 3B
- Proteinase K
- Proteinuria
- Proteoglycan 3
- Proteoglycan 4
- Proteolipid Protein 1
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- Prothrombin Fragment 1+2,F1+2
- Protocadherin 1
- Protocadherin 10
- Protocadherin 8
- Protocadherin 9
- Protocadherin gamma
- Protocadherin gamma 12
- Protocadherin gamma Subfamily A, 4
- Protocadherin gamma Subfamily C, 3
- PROX1
- PROX2
- PROZ
- PRP1
- PRP19
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