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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins

(Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The expression of this gene is induced in a p53-dependent manner in response to various environmental stresses. While being induced by tumor suppressor protein TP53/p53, this phosphatase negatively regulates the activity of p38 MAP kinase, MAPK/p38, through which it reduces the phosphorylation of p53, and in turn suppresses p53-mediated transcription and apoptosis. This phosphatase thus mediates a feedback regulation of p38-p53 signaling that contributes to growth inhibition and the suppression of stress induced apoptosis. This gene is located in a chromosomal region known to be amplified in breast cancer. The amplification of this gene has been detected in both breast cancer cell line and primary breast tumors, which suggests a role of this gene in cancer development. [provided by RefSeq, Jul 2008].
PPM1D Protein (AA 496-605) (GST tag) PPM1D Protein (AA 496-605) (GST tag) PPM1D Protein (AA 496-605) (GST tag) (ABIN1315910)

PPM1D Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

PPM1D Protein (AA 1-605) (GST tag) PPM1D Protein (AA 1-605) (GST tag) PPM1D Protein (AA 1-605) (GST tag) (ABIN1315909)

PPM1D Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

PPM1D Protein (AA 98-375) (His tag) (ABIN5623952)

PPM1D Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % pure SDS

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins by Origin

Find Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins for a variety of species such as anti-Human Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D, anti-Mouse Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D. The species listed below are among those available. Click on a link to go to the corresponding products.

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins by Source

Here you will find Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins by Protein Type

Here you can find Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins by Application

Find Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315910
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315909
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN5623952
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3086448
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3130585
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2729806
Quantity 20 μg
Datasheet Datasheet

Aliases for Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D Proteins

protein phosphatase, Mg2+/Mn2+ dependent 1D (PPM1D) Proteins
protein phosphatase 1D magnesium-dependent, delta isoform (Ppm1d) Proteins
protein phosphatase, Mg2+/Mn2+ dependent, 1D (Ppm1d) Proteins
protein phosphatase, Mg2+/Mn2+ dependent, 1Db (ppm1db) Proteins
protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog (ppm1d.L) Proteins
protein phosphatase, Mg2+/Mn2+ dependent, 1Da (ppm1da) Proteins
AV338790 Proteins
PP2C-DELTA Proteins
ppm1d Proteins
WIP1 Proteins
Wip1 Proteins
wu:fj44c08 Proteins
zgc:55836 Proteins
zgc:77316 Proteins
zgc:103518 Proteins

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