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Prostaglandin E Synthase Products

(Prostaglandin E Synthase (PTGES))

Categories

The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008].

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Featured Prostaglandin E Synthase Categories

Prostaglandin E Synthase Antibodies

High quality antibodies with extensive validation data.

Prostaglandin E Synthase ELISA Kits

Reliable ELISA kits for a wide range of species.

Prostaglandin E Synthase Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Prostaglandin E Synthase Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IP
Validations
  • (5)
Cat. No. ABIN523024
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (3)
Cat. No. ABIN735788
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rabbit
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN1923233
Quantity 50 μg
Datasheet Datasheet

Recommended Prostaglandin E Synthase ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958866
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969652
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969651
Quantity 96 tests
Datasheet Datasheet

Recommended Prostaglandin E Synthase Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316736
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316738
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7410565
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Prostaglandin E Synthase products

Kim, Roszik, Cho, Ogata, Milton, Peng, Menter, Ekmekcioglu, Grimm: "The COX2 Effector Microsomal PGE2 Synthase 1 is a Regulator of Immunosuppression in Cutaneous Melanoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 25, Issue 5, pp. 1650-1663, (2019) (PubMed).

Kim, Hashimoto, Cho, Roszik, Milton, Dal, Kim, Menter, Yang, Ekmekcioglu, Grimm: "Microsomal PGE2 synthase-1 regulates melanoma cell survival and associates with melanoma disease progression." in: Pigment cell & melanoma research, Vol. 29, Issue 3, pp. 297-308, (2016) (PubMed).

Yao, Chen, Han, Wu: "Microsomal prostaglandin E synthase-1 protects against Fas-induced liver injury." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 310, Issue 11, pp. G1071-80, (2016) (PubMed).

Yu, Hou, Sun, Liu, Li et al.: "Upregulation of C-C chemokine receptor type 7 expression by membrane-associated prostaglandin E synthase-1/prostaglandin E2 requires glycogen synthase kinase 3β-mediated signal transduction in colon ..." in: Molecular medicine reports, Vol. 12, Issue 5, pp. 7169-75, (2015) (PubMed).

Sakumoto, Hayashi, Takahashi: "Different expression of PGE synthase, PGF receptor, TNF, Fas and oxytocin in the bovine corpus luteum of the estrous cycle and pregnancy." in: Reproductive biology, Vol. 14, Issue 2, pp. 115-21, (2014) (PubMed).

Dilmé, Solà-Villà, Bellmunt, Romero, Escudero, Camacho, Vila: "Active smoking increases microsomal PGE2-synthase-1/PGE-receptor-4 axis in human abdominal aortic aneurysms." in: Mediators of inflammation, Vol. 2014, pp. 316150, (2014) (PubMed).

Wang, Guan, Wang, Yu, Guo, Wang: "Aggravation of Alzheimer's disease due to the COX-2-mediated reciprocal regulation of IL-1β and Aβ between glial and neuron cells." in: Aging cell, Vol. 13, Issue 4, pp. 605-15, (2014) (PubMed).

Camacho, Dilmé, Solà-Villà, Rodríguez, Bellmunt, Siguero, Alcolea, Romero, Escudero, Martínez-González, Vila: "Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm." in: Journal of lipid research, Vol. 54, Issue 12, pp. 3506-15, (2013) (PubMed).

Nakanishi, Menoret, Tanaka, Miyamoto, Montrose, Vella, Rosenberg: "Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity." in: Cancer prevention research (Philadelphia, Pa.), Vol. 4, Issue 8, pp. 1198-208, (2011) (PubMed).

Synonyms and alternative names related to Prostaglandin E Synthase

prostaglandin E synthase (PTGES), prostaglandin E synthase S homeolog (ptges.S), prostaglandin E synthase (Ptges), 2410099E23Rik, D2Ertd369e, MGC80290, MGST-IV, MGST1-L1, MGST1L1, MPGES, mPGES, mPGES-1, MPGES-1, PGES, Pges, PIG12, PP102, PP1294, ptges, PTGES, TP53I12

Protein level used designations for Prostaglandin E Synthase

  • microsomal prostaglandin E synthase-1
  • prostaglandin E synthase
  • MGST1-like 1
  • glutathione S-transferase 1-like 1
  • microsomal glutathione S-transferase 1-like 1
  • microsomal prostaglandin E synthase 1
  • p53-induced apoptosis protein 12
  • p53-induced gene 12 protein
  • tumor protein p53 inducible protein 12
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