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PROK2 Products

(Prokineticin 2 (PROK2))
This gene encodes a protein expressed in the suprachiasmatic nucleus (SCN) circadian clock that may function as the output component of the circadian clock. The secreted form of the encoded protein may also serve as a chemoattractant for neuronal precursor cells in the olfactory bulb. Proteins from other vertebrates which are similar to this gene product were isolated based on homology to snake venom and secretions from frog skin, and have been shown to have diverse functions. Mutations in this gene are associated with Kallmann syndrome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured PROK2 Categories

PROK2 Antibodies

High quality antibodies with extensive validation data.

PROK2 ELISA Kits

Reliable ELISA kits for a wide range of species.

PROK2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PROK2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7431077
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN6146244
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7431080
Quantity 100 μL
Datasheet Datasheet

Recommended PROK2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969586
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969587
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969585
Quantity 96 tests
Datasheet Datasheet

Recommended PROK2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124582
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316366
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN935716
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our PROK2 products

Frondelli, Levison: "Leukemia Inhibitory Factor Is Required for Subventricular Zone Astrocyte Progenitor Proliferation and for Prokineticin-2 Production after a Closed Head Injury in Mice." in: Neurotrauma reports, Vol. 2, Issue 1, pp. 285-302, (2021) (PubMed).

Ma, Li, Wu, Zhang, Shen, Li, Wang, Chen: "Roles of Prokineticin 2 in Subarachnoid Hemorrhage-Induced Early Brain Injury via Regulation of Phenotype Polarization in Astrocytes." in: Molecular neurobiology, Vol. 57, Issue 9, pp. 3744-3758, (2020) (PubMed).

Yoshida, Goi, Kurebayashi, Morikawa, Hirono, Katayama: "Prokineticin 2 expression as a novel prognostic biomarker for human colorectal cancer." in: Oncotarget, Vol. 9, Issue 53, pp. 30079-30091, (2018) (PubMed).

Xiao, Li, Jones-Brando, Yolken: "Abnormalities of neurotransmitter and neuropeptide systems in human neuroepithelioma cells infected by three Toxoplasma strains." in: Journal of neural transmission (Vienna, Austria : 1996), Vol. 120, Issue 12, pp. 1631-9, (2013) (PubMed).

Urayama, Guilini, Messaddeq, Hu, Steenman, Kurose, Ert, Nebigil: "The prokineticin receptor-1 (GPR73) promotes cardiomyocyte survival and angiogenesis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 11, pp. 2980-93, (2007) (PubMed).

Pitteloud, Zhang, Pignatelli, Li, Raivio, Cole, Plummer, Jacobson-Dickman, Mellon, Zhou, Crowley: "Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 44, pp. 17447-52, (2007) (PubMed).

Synonyms and alternative names related to PROK2

prokineticin 2 (PROK2), prokineticin 2 (prok2), prokineticin 2 S homeolog (prok2.S), prokineticin 2 (Prok2), prokineticin-2 (LOC101104864), Bv8, BV8, HH4, KAL4, MIT1, PK2, Prok1, PROK2

Protein level used designations for PROK2

  • prokineticin 2
  • prokineticin-2
  • PK2
  • homolog of mouse Bv8 (Bombina variegata 8 kDa)
  • homolog of mouse Bv8 (Bombina variegata 8 kDa); prokineticin 2
  • prokineticin 2 beta
  • Bombina variegata 8 kD protein
  • Bombina variegata 8kDa protein
  • Bv 8 homolog (Bombina variegata)
  • prokineticin 1
  • protein Bv8 homolog
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