PRMT6 Products
(Protein Arginine Methyltransferase 6 (PRMT6))
Categories
The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011].
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Featured PRMT6 Categories
PRMT6 Antibodies
High quality antibodies with extensive validation data.
PRMT6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PRMT6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
Cat. No.
ABIN949428
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (5)
Cat. No.
ABIN3032363
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7165075
Quantity
100 μg
Datasheet
Datasheet
Recommended PRMT6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951336
Quantity
96 tests
Datasheet
Datasheet
Recommended PRMT6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124643
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316337
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316339
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PRMT6 products
: "The methyltransferase PRMT6 attenuates antiviral innate immunity by blocking TBK1-IRF3 signaling." in: Cellular & molecular immunology, (2018) (PubMed).: "PRMT4 is involved in insulin secretion via the methylation of histone H3 in pancreatic β cells." in: Journal of molecular endocrinology, Vol. 54, Issue 3, pp. 315-24, (2015) (PubMed).
: "PELP1 oncogenic functions involve alternative splicing via PRMT6." in: Molecular oncology, Vol. 8, Issue 2, pp. 389-400, (2014) (PubMed).
: "A gain-of-function mouse model identifies PRMT6 as a NF-κB coactivator." in: Nucleic acids research, Vol. 42, Issue 13, pp. 8297-309, (2014) (PubMed).
: "Ablation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressor." in: Nucleic acids research, Vol. 40, Issue 19, pp. 9513-21, (2012) (PubMed).
: "Activity-based protein profiling of protein arginine methyltransferase 1." in: ACS chemical biology, Vol. 6, Issue 10, pp. 1127-35, (2011) (PubMed).
: "Regulation of post-translational protein arginine methylation during HeLa cell cycle." in: Biochimica et biophysica acta, Vol. 1800, Issue 9, pp. 977-85, (2010) (PubMed).
: "Proteomic identification and comparative analysis of asymmetrically arginine-methylated proteins in immortalized, young and senescent cells." in: Electrophoresis, Vol. 31, Issue 23-24, pp. 3823-33, (2010) (PubMed).
: "Arginine methylation regulates telomere length and stability." in: Molecular and cellular biology, Vol. 29, Issue 18, pp. 4918-34, (2009) (PubMed).
: "Human protein arginine methyltransferases in vivo--distinct properties of eight canonical members of the PRMT family." in: Journal of cell science, Vol. 122, Issue Pt 5, pp. 667-77, (2009) (PubMed).
Synonyms and alternative names related to PRMT6
Arginine methyltransferase 6 (Art6), protein arginine methyltransferase 6 (PRMT6), protein arginine methyltransferase 6 S homeolog (prmt6.S), arginine N-methyltransferase, type I (PRMT6), protein arginine methyltransferase 6 (prmt6), protein arginine methyltransferase 6 (Prmt6), protein arginine N-methyltransferase 6 (Prmt6), ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 6, ATPRMT6, AW124876, BB233495, CG9927, DART6, DKFZp459B1431, Dmel\\CG9927, HRMT1L6, Hrmt1l6, hrmt1l6, hrmt6, im:6908706, PRMT6, protein arginine methyltransferase 6Protein level used designations for PRMT6
- arginine methyltransferase 6
- CG9927-PA
- Art6-PA
- protein arginine methyltransferase 6
- HMT1 hnRNP methyltransferase-like 6
- Histone-arginine N-methyltransferase PRMT6
- protein arginine N-methyltransferase 6
- arginine N-methyltransferase, type I
- heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6
- histone-arginine N-methyltransferase PRMT6
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