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PRMT6 Products

(Protein Arginine Methyltransferase 6 (PRMT6))

Categories

The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011].

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Featured PRMT6 Categories

PRMT6 Antibodies

High quality antibodies with extensive validation data.

PRMT6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PRMT6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (5)
Cat. No. ABIN949428
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (5)
Cat. No. ABIN3032363
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7165075
Quantity 100 μg
Datasheet Datasheet

Recommended PRMT6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951336
Quantity 96 tests
Datasheet Datasheet

Recommended PRMT6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124643
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316337
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316339
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PRMT6 products

Zhang, Han, Li, Li, Cao: "The methyltransferase PRMT6 attenuates antiviral innate immunity by blocking TBK1-IRF3 signaling." in: Cellular & molecular immunology, (2018) (PubMed).

Kim, Lim, Lee, Lee, Won, Kim, Kim: "PRMT4 is involved in insulin secretion via the methylation of histone H3 in pancreatic β cells." in: Journal of molecular endocrinology, Vol. 54, Issue 3, pp. 315-24, (2015) (PubMed).

Mann, Zou, Chen, Brann, Vadlamudi: "PELP1 oncogenic functions involve alternative splicing via PRMT6." in: Molecular oncology, Vol. 8, Issue 2, pp. 389-400, (2014) (PubMed).

Di Lorenzo, Yang, Macaluso, Bedford: "A gain-of-function mouse model identifies PRMT6 as a NF-κB coactivator." in: Nucleic acids research, Vol. 42, Issue 13, pp. 8297-309, (2014) (PubMed).

Neault, Mallette, Vogel, Michaud-Levesque, Richard: "Ablation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressor." in: Nucleic acids research, Vol. 40, Issue 19, pp. 9513-21, (2012) (PubMed).

Obianyo, Causey, Jones, Thompson: "Activity-based protein profiling of protein arginine methyltransferase 1." in: ACS chemical biology, Vol. 6, Issue 10, pp. 1127-35, (2011) (PubMed).

Kim, Lim, Yoo, Won, Kim, Kim: "Regulation of post-translational protein arginine methylation during HeLa cell cycle." in: Biochimica et biophysica acta, Vol. 1800, Issue 9, pp. 977-85, (2010) (PubMed).

Lim, Hong, Kwon, Lee: "Proteomic identification and comparative analysis of asymmetrically arginine-methylated proteins in immortalized, young and senescent cells." in: Electrophoresis, Vol. 31, Issue 23-24, pp. 3823-33, (2010) (PubMed).

Mitchell, Glenfield, Jeyanthan, Zhu: "Arginine methylation regulates telomere length and stability." in: Molecular and cellular biology, Vol. 29, Issue 18, pp. 4918-34, (2009) (PubMed).

Herrmann, Pably, Eckerich, Bedford, Fackelmayer: "Human protein arginine methyltransferases in vivo--distinct properties of eight canonical members of the PRMT family." in: Journal of cell science, Vol. 122, Issue Pt 5, pp. 667-77, (2009) (PubMed).

Synonyms and alternative names related to PRMT6

Arginine methyltransferase 6 (Art6), protein arginine methyltransferase 6 (PRMT6), protein arginine methyltransferase 6 S homeolog (prmt6.S), arginine N-methyltransferase, type I (PRMT6), protein arginine methyltransferase 6 (prmt6), protein arginine methyltransferase 6 (Prmt6), protein arginine N-methyltransferase 6 (Prmt6), ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 6, ATPRMT6, AW124876, BB233495, CG9927, DART6, DKFZp459B1431, Dmel\\CG9927, HRMT1L6, Hrmt1l6, hrmt1l6, hrmt6, im:6908706, PRMT6, protein arginine methyltransferase 6

Protein level used designations for PRMT6

  • arginine methyltransferase 6
  • CG9927-PA
  • Art6-PA
  • protein arginine methyltransferase 6
  • HMT1 hnRNP methyltransferase-like 6
  • Histone-arginine N-methyltransferase PRMT6
  • protein arginine N-methyltransferase 6
  • arginine N-methyltransferase, type I
  • heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6
  • histone-arginine N-methyltransferase PRMT6
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