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PRKAG2 Products

(Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))

Categories

AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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Featured PRKAG2 Categories

PRKAG2 Antibodies

High quality antibodies with extensive validation data.

PRKAG2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PRKAG2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN2856952
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (4)
Cat. No. ABIN526709
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC, IHC (p)
Validations
  • (3)
Cat. No. ABIN2856652
Quantity 100 μL
Datasheet Datasheet

Recommended PRKAG2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316237
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316235
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405708
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PRKAG2 products

Pinter, Jefferson, Czibik, Watkins, Redwood: "Subunit composition of AMPK trimers present in the cytokinetic apparatus: Implications for drug target identification." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 5, pp. 917-21, (2012) (PubMed).

Lin, Kiihl, Suhail, Liu, Chou, Kuang, Lu, Khor, Lin, Bader, Irizarry, Boeke: "Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK." in: Nature, Vol. 482, Issue 7384, pp. 251-5, (2012) (PubMed).

Martiáñez, Francès, López: "Generation of digital responses in stress sensors." in: The Journal of biological chemistry, Vol. 284, Issue 36, pp. 23902-11, (2009) (PubMed).

Vaughan, Hom, Okin, McDermott, Lerman, Basson: "Molecular genetic analysis of PRKAG2 in sporadic Wolff-Parkinson-White syndrome." in: Journal of cardiovascular electrophysiology, Vol. 14, Issue 3, pp. 263-8, (2003) (PubMed).

Daniel, Carling: "Functional analysis of mutations in the gamma 2 subunit of AMP-activated protein kinase associated with cardiac hypertrophy and Wolff-Parkinson-White syndrome." in: The Journal of biological chemistry, Vol. 277, Issue 52, pp. 51017-24, (2002) (PubMed).

Gollob, Green, Tang, Roberts: "PRKAG2 cardiac syndrome: familial ventricular preexcitation, conduction system disease, and cardiac hypertrophy." in: Current opinion in cardiology, Vol. 17, Issue 3, pp. 229-34, (2002) (PubMed).

Tobias, Lazauskas, Arevalo, Bagley, Brown, Galpin: "Fiber type-specific analysis of AMPK isoforms in human skeletal muscle: advancement in methods via capillary nano-immunoassay." in: Journal of applied physiology (Bethesda, Md. : 1985) (PubMed).

Synonyms and alternative names related to PRKAG2

protein kinase AMP-activated non-catalytic subunit gamma 2 (Prkag2), protein kinase AMP-activated non-catalytic subunit gamma 2 (PRKAG2), protein kinase, AMP-activated, gamma 2 non-catalytic subunit L homeolog (prkag2.L), 5'-AMP-activated protein kinase subunit gamma-2 (LOC504219), protein kinase, AMP-activated, gamma 2 non-catalytic subunit b (prkag2b), protein kinase, AMP-activated, gamma 2 non-catalytic subunit (prkag2), protein kinase, AMP-activated, gamma 2 non-catalytic subunit (Prkag2), 2410051C13Rik, AAKG, AAKG2, AI854673, CMH6, H91620p, MGC82938, PRKAG2, si:ch211-230l11.1, si:dkey-217f4.2, WPWS

Protein level used designations for PRKAG2

  • 5'-AMP-activated protein kinase subunit gamma-2
  • AMP-activated protein kinase gamma2 subunit
  • AMPK gamma 2
  • adenosine monophosphate-activated protein kinase gamma 2-subunit
  • 5'-AMP-activated protein kinase gamma-2 non-catalytic subunit
  • protein kinase, AMP-activated, gamma 2 non-catalytic subunit
  • AMPK-activated protein kinase gamma-2 subunit
  • AMPK subunit gamma-2
  • 5-AMP-activated protein kinase, gamma-2 subunit
  • AMPK gamma-2 chain
  • AMPK gamma2
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