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PRKACB Products

(Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Several alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jun 2011].

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Featured PRKACB Categories

PRKACB Antibodies

High quality antibodies with extensive validation data.

PRKACB ELISA Kits

Reliable ELISA kits for a wide range of species.

PRKACB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PRKACB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN6146183
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7146602
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6257011
Quantity 100 μL
Datasheet Datasheet

Recommended PRKACB ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965375
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965373
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965374
Quantity 96 tests
Datasheet Datasheet

Recommended PRKACB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316227
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316225
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5509097
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PRKACB products

Dwivedi, Rizavi, Shukla, Lyons, Faludi, Palkovits, Sarosi, Conley, Roberts, Tamminga, Pandey: "Protein kinase A in postmortem brain of depressed suicide victims: altered expression of specific regulatory and catalytic subunits." in: Biological psychiatry, Vol. 55, Issue 3, pp. 234-43, (2004) (PubMed).

Higuchi, Yamashita, Yoshikawa, Tohyama: "PKA phosphorylates the p75 receptor and regulates its localization to lipid rafts." in: The EMBO journal, Vol. 22, Issue 8, pp. 1790-800, (2003) (PubMed).

Cartier, Hemonnot, Gay, Bardy, Sanchiz, Devaux, Briant: "Active cAMP-dependent protein kinase incorporated within highly purified HIV-1 particles is required for viral infectivity and interacts with viral capsid protein." in: The Journal of biological chemistry, Vol. 278, Issue 37, pp. 35211-9, (2003) (PubMed).

Synonyms and alternative names related to PRKACB

protein kinase cAMP-activated catalytic subunit beta (PRKACB), protein kinase cAMP-activated catalytic subunit beta S homeolog (prkacb.S), protein kinase, cAMP-dependent, catalytic, beta (PRKACB), protein kinase cAMP-activated catalytic subunit beta (prkacb), protein kinase cAMP-activated catalytic subunit beta (Prkacb), protein kinase, cAMP-dependent, catalytic, beta b (prkacbb), protein kinase, cAMP dependent, catalytic, beta (Prkacb), kin-1, PKACB, pkacb, Pkacb, PRKACB, prkacb, prkacba, wu:fz54b03, XPKAbeta, zgc:110804

Protein level used designations for PRKACB

  • PKA C-beta
  • cAMP-dependent protein kinase catalytic beta subunit isoform 4ab
  • cAMP-dependent protein kinase catalytic subunit beta
  • protein kinase A catalytic subunit beta
  • p70 S6 kinase
  • protein kinase, cAMP-dependent, catalytic, beta a
  • C-beta subunit
  • protein kinase, cAMP-dependent, catalytic, beta
  • cAMP-dependent protein kinase C beta
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