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PREX1 Products

(Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

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The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008].

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Featured PREX1 Categories

PREX1 Antibodies

High quality antibodies with extensive validation data.

PREX1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended PREX1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (5)
Cat. No. ABIN656506
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7163177
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC
Validations
  • (2)
Cat. No. ABIN6264416
Quantity 100 μL
Datasheet Datasheet

Recommended PREX1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969255
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6233636
Quantity 96 tests
Datasheet Datasheet

Recommended PREX1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2751156
Quantity 5 applications
Datasheet Datasheet

Latest Publications for our PREX1 products

Campbell, Lawn, McGarry, Welch, Ozanne, Norman: "P-Rex1 cooperates with PDGFRβ to drive cellular migration in 3D microenvironments." in: PLoS ONE, Vol. 8, Issue 1, pp. e53982, (2013) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Lindsay, Lawn, Campbell, Faller, Rambow, Mort, Timpson, Li, Cammareri, Ridgway, Morton, Doyle, Hegarty, Rafferty, Murphy, McDermott, Sheahan, Pedone, Finn, Groben, Thomas, Hao, Carson, Norman et al.: "P-Rex1 is required for efficient melanoblast migration and melanoma metastasis. ..." in: Nature communications, Vol. 2, pp. 555, (2011) (PubMed).

Qin, Xie, Wang, Hoshino, Wolff, Zhao, Scofield, Dowd, Lin, Tu: "Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis." in: Oncogene, Vol. 28, Issue 16, pp. 1853-63, (2009) (PubMed).

Synonyms and alternative names related to PREX1

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 L homeolog (prex1.L), phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 (PREX1), phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (prex1), phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 (prex1), phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (Prex1), G630042G04, MGC68772, P-REX1, RGD1306534, Setd6

Protein level used designations for PREX1

  • phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
  • phosphatidylinositol 3,4,5-trisphosphate-dependent RAC exchanger 1
  • phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein-like
  • phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
  • ptdIns(3,4,5)-dependent Rac exchanger 1
  • SET domain containing 6
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