PPY Products
(Pancreatic Polypeptide (PPY))
Categories
This gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products\; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. [provided by RefSeq, Jul 2008].
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Featured PPY Categories
PPY Antibodies
High quality antibodies with extensive validation data.
PPY ELISA Kits
Reliable ELISA kits for a wide range of species.
PPY Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PPY Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (2)
- (3)
Cat. No.
ABIN1098139
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC, FACS, IF
Validations
- (1)
- (2)
Cat. No.
ABIN185420
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7433351
Quantity
100 μL
Datasheet
Datasheet
Recommended PPY ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969135
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
Cat. No.
ABIN6969134
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962535
Quantity
96 tests
Datasheet
Datasheet
Recommended PPY Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124305
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316102
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN1945400
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our PPY products
: "Transgenic substitution with Greater Amberjack Seriola dumerili fish insulin 2 in NOD mice reduces beta cell immunogenicity." in: Scientific reports, Vol. 9, Issue 1, pp. 4965, (2019) (PubMed).: "Development of monoclonal mouse antibodies that specifically recognize pancreatic polypeptide." in: Endocrine journal, Vol. 66, Issue 5, pp. 459-468, (2019) (PubMed).
: "The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes." in: Cell metabolism, Vol. 27, Issue 6, pp. 1294-1308.e7, (2018) (PubMed).
: "Islet Interleukin-1β Immunoreactivity Is an Early Feature of Cystic Fibrosis That May Contribute to β-Cell Failure." in: Diabetes Care, Vol. 41, Issue 4, pp. 823-830, (2018) (PubMed).
: "Pancreatic Nonhormone Expressing Endocrine Cells in Children With Type 1 Diabetes." in: Journal of the Endocrine Society, Vol. 1, Issue 5, pp. 385-395, (2017) (PubMed).
: "Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes." in: The Journal of clinical endocrinology and metabolism, Vol. 101, Issue 3, pp. 1044-54, (2016) (PubMed).
: "Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice." in: Nature communications, Vol. 7, pp. 12631, (2016) (PubMed).
: "The polyphenol (-)-epigallocatechin-3-gallate prevents apoA-IIowa amyloidosis in vitro and protects human embryonic kidney 293 cells against amyloid cytotoxicity." in: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, Vol. 23, Issue 1, pp. 17-25, (2016) (PubMed).
: "Delta Cell Hyperplasia in Adult Goto-Kakizaki (GK/MolTac) Diabetic Rats." in: Journal of diabetes research, Vol. 2015, pp. 385395, (2015) (PubMed).
: "New perspectives of vesicular monoamine transporter 2 chemical characteristics in mammals and its constant expression in type 1 diabetes rat models." in: Translational research : the journal of laboratory and clinical medicine, Vol. 163, Issue 2, pp. 171-82, (2014) (PubMed).
Synonyms and alternative names related to PPY
pancreatic polypeptide (PPY), pancreatic polypeptide (Ppy), peptide YY (PYY), AV061413, IGSPP, PNP, PP, PPYProtein level used designations for PPY
- pancreatic polypeptide
- PP
- pancreatic polypeptide Y
- pancreatic prohormone
- prepro-PP (prepropancreatic polypeptide)
- Pancreatic prohormone percursor
- panceatic polypeptide
- pancreatic hormone
- seminalplasmin
- Pancreatic prohormone
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