PPP2R2B Products
(Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))
Categories
The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 66-78 copies in cases of SCA12. [provided by RefSeq, Jul 2008].
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Featured PPP2R2B Categories
PPP2R2B Antibodies
High quality antibodies with extensive validation data.
PPP2R2B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PPP2R2B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (4)
Cat. No.
ABIN519118
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF, IHC
Validations
- (3)
Cat. No.
ABIN7169246
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
Cat. No.
ABIN652541
Quantity
400 μL
Datasheet
Datasheet
Recommended PPP2R2B ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6231900
Quantity
96 tests
Datasheet
Datasheet
Recommended PPP2R2B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316024
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316026
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316028
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PPP2R2B products
: "Combined inhibition of EZH2 and histone deacetylases as a potential epigenetic therapy for non-small-cell lung cancer cells." in: Cancer science, Vol. 107, Issue 7, pp. 955-62, (2016) (PubMed).Synonyms and alternative names related to PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta (PPP2R2B), protein phosphatase 2, regulatory subunit B, beta (Ppp2r2b), protein phosphatase 2 regulatory subunit B, beta L homeolog (ppp2r2b.L), protein phosphatase 2 regulatory subunit B, beta (ppp2r2b), protein phosphatase 2, regulatory subunit B, beta b (ppp2r2bb), protein phosphatase 2 regulatory subunit Bbeta (Ppp2r2b), 2900026H06Rik, 6330404L05Rik, B55BETA, E130009M08Rik, PP2A, PP2A-PR55B, PP2AB55BETA, PP2ABBETA, PP2APR55B, PP2APR55BETA, ppp2r2b, PPP2R2B, ppp2r2b-a, ppp2r2c, Pppr2b2, PR2AB55BETA, PR2ABBETA, PR2APR55BETA, PR52B, PR55-BETA, PR55BETA, SCA12, zgc:101861Protein level used designations for PPP2R2B
- PP2A subunit B isoform B55-beta
- PP2A subunit B isoform PR55-beta
- PP2A subunit B isoform R2-beta
- PP2A, subunit B, B-beta isoform
- protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
- protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform
- serine/threonine protein phosphatase 2A, 55 kDa regulatory subunit B, beta isoform
- serine/threonine protein phosphatase 2A, neuronal isoform
- serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
- BRbeta B-regulatory subunit of protein phosphatase 2A
- PP2A subunit B isoform BRB
- PP2A subunit B isoform beta
- PP2A, subunit B, B55-beta isoform
- PP2A, subunit B, BRB isoform
- PP2A, subunit B, PR55-beta isoform
- PP2A, subunit B, R2-beta isoform
- phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
- protein phosphatase 2A 55 kDa regulatory subunit, beta isoform
- beta isoform of regulatory subunit B55, protein phosphatase 2
- protein phosphatase-2A subunit-beta
- protein phosphatase 2, regulatory subunit B, beta
- serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform-like
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