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PPARD Products

(Peroxisome Proliferator-Activated Receptor delta (PPARD))
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010].

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Featured PPARD Categories

PPARD Antibodies

High quality antibodies with extensive validation data.

PPARD ELISA Kits

Reliable ELISA kits for a wide range of species.

PPARD Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PPARD Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (1)
  • (4)
Cat. No. ABIN562332
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA
Validations
  • (1)
  • (3)
Cat. No. ABIN105799
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6264373
Quantity 100 μL
Datasheet Datasheet

Recommended PPARD ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969235
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958501
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958502
Quantity 96 tests
Datasheet Datasheet

Recommended PPARD Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315833
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315832
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505069
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PPARD products

Matsushita, Hassanein, Martinez-Clemente, Lazaro, French, Xie, Lai, Karin, Tsukamoto: "Gender difference in NASH susceptibility: Roles of hepatocyte Ikkβ and Sult1e1." in: PLoS ONE, Vol. 12, Issue 8, pp. e0181052, (2017) (PubMed).

Kramerova, Ermolova, Eskin, Hevener, Quehenberger, Armando, Haller, Romain, Nelson, Spencer: "Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy)." in: Human molecular genetics, Vol. 25, Issue 11, pp. 2194-2207, (2016) (PubMed).

Falcone, Florio, Di Giacomo, Benedetti, Cristiano, Antonosante, Fidoamore, Massimi, Alecci, Ippoliti, Giordano, Cimini: "PPARβ/δ and γ in a rat model of Parkinson's disease: possible involvement in PD symptoms." in: Journal of cellular biochemistry, Vol. 116, Issue 5, pp. 844-55, (2015) (PubMed).

Kotla, Rao: "Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell Formation." in: The Journal of biological chemistry, Vol. 290, Issue 51, pp. 30306-20, (2015) (PubMed).

Castillero, Alamdari, Aversa, Gurav, Hasselgren: "PPARβ/δ regulates glucocorticoid- and sepsis-induced FOXO1 activation and muscle wasting." in: PLoS ONE, Vol. 8, Issue 3, pp. e59726, (2013) (PubMed).

Ares-Carrasco, Picatoste, Camafeita, Carrasco-Navarro, Zubiri, Ortiz, Egido, López, Tuñón, Lorenzo: "Proteome changes in the myocardium of experimental chronic diabetes and hypertension: role of PPAR? in the associated hypertrophy." in: Journal of proteomics, Vol. 75, Issue 6, pp. 1816-29, (2012) (PubMed).

Yang, Zhang, Zhou, Yan, Adell, Sun: "Biological function and prognostic significance of peroxisome proliferator-activated receptor ? in rectal cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 11, pp. 3760-70, (2011) (PubMed).

Minamiyama, Takemura, Kodai, Shinkawa, Tsukioka, Ichikawa, Naito, Yoshikawa, Okada: "Iron restriction improves type 2 diabetes mellitus in Otsuka Long-Evans Tokushima fatty rats." in: American journal of physiology. Endocrinology and metabolism, Vol. 298, Issue 6, pp. E1140-9, (2010) (PubMed).

Yang, Olsson, Pfeifer, Jönsson, Zhou, Jiang, Fredriksson, Zhang, Sun: "Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell-fibronectin adhesion of colon cancer cells." in: Oncogene, Vol. 29, Issue 4, pp. 516-26, (2010) (PubMed).

Holloway, Perry, Thrush, Heigenhauser, Dyck, Bonen, Spriet: "PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 6, pp. E1060-9, (2008) (PubMed).

Synonyms and alternative names related to PPARD

peroxisome proliferator activated receptor delta (PPARD), peroxisome proliferator activator receptor delta (Ppard), peroxisome proliferator activated receptor delta S homeolog (ppard.S), peroxisome proliferator activated receptor delta (ppard), peroxisome proliferator-activated receptor delta (Ppard), peroxisome proliferator activated receptor delta (Ppard), FAAR, NR1C2, Nr1c2, NUC-1, NUC1, NUCI, NUCII, PPAR-beta, PPAR-D/B, PPAR-delta, PPARB, Pparb, pparb, Pparb/d, PPARBETA, ppard, PPARD, PPARdelta, PPAR[b]

Protein level used designations for PPARD

  • PPAR-beta
  • PPAR-delta
  • nuclear hormone receptor 1
  • nuclear receptor subfamily 1 group C member 2
  • peroxisome proliferator-activated nuclear receptor beta/delta variant 2
  • peroxisome proliferator-activated receptor beta
  • PPARdelta/beta
  • Peroxisome proliferator-activated receptor beta
  • peroxisome proliferator-activated receptor delta
  • peroxisome proliferative activated receptor, delta
  • peroxisome proliferator-activated receptor delta-like
  • peroxisome proliferator activated receptor delta
  • peroxisome proliferator activator receptor beta
  • peroxisome proliferator activator receptor, delta
  • peroxisome proliferator activator receptor delta
  • peroxisome proliferator activated receptor delta/beta
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