PPARA Products
(Peroxisome Proliferator-Activated Receptor alpha (PPARA))
Categories
Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers\; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008].
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Featured PPARA Categories
PPARA Antibodies
High quality antibodies with extensive validation data.
PPARA ELISA Kits
Reliable ELISA kits for a wide range of species.
PPARA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PPARA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Chicken, Human, Mouse, Rat
Application
WB, ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
- (1)
- (5)
Cat. No.
ABIN701620
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, FACS, IF, IHC (p)
Validations
- (4)
- (5)
Cat. No.
ABIN1944858
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7432904
Quantity
100 μL
Datasheet
Datasheet
Recommended PPARA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958498
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6958500
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969234
Quantity
96 tests
Datasheet
Datasheet
Recommended PPARA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315830
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124374
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505511
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PPARA products
: "Branched chain amino acids exacerbate myocardial ischemia/reperfusion vulnerability via enhancing GCN2/ATF6/PPAR-α pathway-dependent fatty acid oxidation." in: Theranostics, Vol. 10, Issue 12, pp. 5623-5640, (2021) (PubMed).: "Augmenter of liver regeneration protein deficiency promotes hepatic steatosis by inducing oxidative stress and microRNA-540 expression." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 3, pp. 3825-3840, (2019) (PubMed).
: "Troglitazone activates TRPV1 and causes deacetylation of PPARγ in 3T3-L1 cells." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1865, Issue 2, pp. 445-453, (2019) (PubMed).
: "CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis." in: JCI insight, Vol. 5, (2019) (PubMed).
: "Elevated lipolysis in adipose tissue by doxorubicin via PPARα activation associated with hepatic steatosis and insulin resistance." in: European journal of pharmacology, Vol. 843, pp. 162-176, (2019) (PubMed).
: "Cellular Distribution of Canonical and Putative Cannabinoid Receptors in Canine Cervical Dorsal Root Ganglia." in: Frontiers in veterinary science, Vol. 6, pp. 313, (2019) (PubMed).
: "Unlike PPARgamma, neither other PPARs nor PGC-1alpha is elevated in the cerebrospinal fluid of patients with multiple sclerosis." in: Neuroscience letters, Vol. 651, pp. 128-133, (2018) (PubMed).
: "Acetic Acid Influences BRL-3A Cell Lipid Metabolism via the AMPK Signalling Pathway." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 45, Issue 5, pp. 2021-2030, (2018) (PubMed).
: "PIK3R3 regulates PPARα expression to stimulate fatty acid β-oxidation and decrease hepatosteatosis." in: Experimental & molecular medicine, Vol. 50, Issue 1, pp. e431, (2018) (PubMed).
: "Localization of cannabinoid receptors CB1, CB2, GPR55, and PPARα in the canine gastrointestinal tract." in: Histochemistry and cell biology, Vol. 150, Issue 2, pp. 187-205, (2018) (PubMed).
Synonyms and alternative names related to PPARA
peroxisome proliferator activated receptor alpha (PPARA), peroxisome proliferator-activated receptor alpha (LOC100136415), peroxisome proliferator activated receptor alpha L homeolog (ppara.L), peroxisome proliferator activated receptor alpha (Ppara), peroxisome proliferator activated receptor alpha (ppara), 4933429D07Rik, AW742785, hPPAR, LOC100136415, NR1C1, nr1c1, Nr1c1, PPAR, Ppar, PPAR-alpha, PPARalpha, PPARALPHA, xppara, xPPARalphaProtein level used designations for PPARA
- PPAR-alpha
- nuclear receptor subfamily 1 group C member 1
- peroxisome proliferative activated receptor, alpha
- peroxisome proliferator-activated nuclear receptor alpha variant 3
- PPAR alpha
- peroxisome proliferator activated receptor alpha
- peroxisome proliferator-activated receptor alpha
- ppar alpha
- xPPAR alpha
- peroxisome proliferator-activated receptor-alpha
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