PP5 Products
(Protein Phosphatase 5, Catalytic Subunit (PPP5C))
Categories
This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues\; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011].
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Featured PP5 Categories
PP5 Antibodies
High quality antibodies with extensive validation data.
PP5 ELISA Kits
Reliable ELISA kits for a wide range of species.
PP5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PP5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IHC (p), FACS
Validations
- (12)
Cat. No.
ABIN1500389
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human
Application
WB, IHC, IF, IHC (p), FACS
Validations
- (15)
Cat. No.
ABIN1500390
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Rat
Application
WB, IHC, IHC (p), FACS
Validations
- (10)
Cat. No.
ABIN1500391
Quantity
100 μL
Datasheet
Datasheet
Recommended PP5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN2748893
Quantity
96 tests
Datasheet
Datasheet
Recommended PP5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1316089
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PP5 products
: "Structural and functional basis of protein phosphatase 5 substrate specificity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 32, pp. 9009-14, (2016) (PubMed).: "Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers." in: eLife, Vol. 3, pp. e01695, (2014) (PubMed).
: "Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent." in: Journal of translational medicine, Vol. 9, pp. 8, (2011) (PubMed).
: "14-3-3 Binding to ataxin-1(ATXN1) regulates its dephosphorylation at Ser-776 and transport to the nucleus." in: The Journal of biological chemistry, Vol. 286, Issue 40, pp. 34606-16, (2011) (PubMed).
: "Molecular basis for TPR domain-mediated regulation of protein phosphatase 5." in: The EMBO journal, Vol. 24, Issue 1, pp. 1-10, (2005) (PubMed).
: "Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity." in: The Journal of biological chemistry, Vol. 279, Issue 35, pp. 36490-6, (2004) (PubMed).
: "Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade." in: The Journal of biological chemistry, Vol. 279, Issue 45, pp. 46595-605, (2004) (PubMed).
: "The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions." in: The EMBO journal, Vol. 17, Issue 5, pp. 1192-9, (1998) (PubMed).
: "The serine/threonine phosphatase PP5 interacts with CDC16 and CDC27, two tetratricopeptide repeat-containing subunits of the anaphase-promoting complex." in: The Journal of biological chemistry, Vol. 272, Issue 51, pp. 32011-8, (1998) (PubMed).
: "Serine/threonine protein phosphatase type 5 acts upstream of p53 to regulate the induction of p21(WAF1/Cip1) and mediate growth arrest." in: The Journal of biological chemistry, Vol. 273, Issue 20, pp. 12250-8, (1998) (PubMed).
Synonyms and alternative names related to PP5
protein phosphatase 5 catalytic subunit (PPP5C), protein phosphatase 5, catalytic subunit (Ppp5c), protein phosphatase 5, catalytic subunit S homeolog (ppp5c.S), protein phosphatase 5, catalytic subunit (ppp5c), serine/threonine-protein phosphatase 5 (LOC592155), serine/threonine-protein phosphatase 5 (LOC100513542), serine/threonine-protein phosphatase 5 (LOC100564151), serine/threonine-protein phosphatase 5 (LOC100186268), serine/threonine-protein phosphatase 5 (LOC100208775), protein phosphatase 5 catalytic subunit (Ppp5c), AU020526, fc83f08, im:7146608, MGC89961, PP5, pp5, PPP5, PPP5C, PPT, wu:fc83f08, zgc:110801Protein level used designations for PP5
- PP-T
- protein phosphatase T
- serine/threonine-protein phosphatase 5
- ANP receptor
- PPT
- PP5
- protein phosphatase 5, catalytic subunit
- serine/threonine-protein phosphatase 5-like
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