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PON1 Products

(Paraoxonase 1 (PON1))
The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. [provided by RefSeq, Oct 2008].

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Featured PON1 Categories

PON1 Antibodies

High quality antibodies with extensive validation data.

PON1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PON1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PON1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (2)
  • (7)
Cat. No. ABIN1724909
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (2)
  • (7)
Cat. No. ABIN1724910
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN7269172
Quantity 100 μL
Datasheet Datasheet

Recommended PON1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
Cat. No. ABIN6720557
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (18)
  • (1)
Cat. No. ABIN6958390
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6962554
Quantity 96 tests
Datasheet Datasheet

Recommended PON1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124313
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315742
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7389626
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PON1 products

Zaragoza-García, Guzmán-Guzmán, Moreno-Godínez, Navarro-Zarza, Antonio-Vejar, Ramírez, Parra-Rojas: "PON-1 haplotype (-108C>T, L55M, and Q192R) modulates the serum levels and activity PONase promoting an atherogenic lipid profile in rheumatoid arthritis patients." in: Clinical rheumatology, Vol. 40, Issue 2, pp. 741-752, (2021) (PubMed).

Wang, Liu, Zhong, Yang, Yang, Covaci, Zhu: "Estimating renal and hepatic clearance rates of organophosphate esters in humans: Impacts of intrinsic metabolism and binding affinity with plasma proteins." in: Environment international, Vol. 134, pp. 105321, (2020) (PubMed).

Lioudaki, Verikokos, Kouraklis, Kontopodis, Markakis, Ioannou, Daskalopoulou, Perrea, Klonaris: "Paraoxonase-1 and Symptomatic Status in Carotid Artery Disease." in: Annals of vascular surgery, Vol. 64, pp. 355-360, (2020) (PubMed).

Halim, Pinkaew, Chunhacha, Sinthujaroen, Thiagarajan, Fujise: "Ticagrelor induces paraoxonase-1 (PON1) and better protects hypercholesterolemic mice against atherosclerosis compared to clopidogrel." in: PLoS ONE, Vol. 14, Issue 6, pp. e0218934, (2019) (PubMed).

Jin, Yang, Su, Ye, Liu, Yang, Wang, Fu, Gong, Sun: "Identification a novel clinical biomarker in early diagnosis of human non-small cell lung cancer." in: Glycoconjugate journal, Vol. 36, Issue 1, pp. 57-68, (2019) (PubMed).

Ahmed: "Correlation of Paraoxonase-1 with glycated hemoglobin and lipid profile among Sudanese diabetic patients." in: Pakistan journal of medical sciences, Vol. 35, Issue 4, pp. 1050-1054, (2019) (PubMed).

Ogłodek: "The role of PON-1, GR, IL-18, and OxLDL in depression with and without posttraumatic stress disorder." in: Pharmacological reports : PR, Vol. 69, Issue 5, pp. 837-845, (2018) (PubMed).

Pop, Niculae, Pop, Răchișan: "Individuals with autism have higher 8-Iso-PGF2α levels than controls, but no correlation with quantitative assay of Paraoxonase 1 serum levels." in: Metabolic brain disease, Vol. 32, Issue 6, pp. 1943-1950, (2018) (PubMed).

Crow, Meek, Wills, Chambers: "A case-control study: The association of serum paraoxonase 1 activity and concentration with the development of type 2 diabetes mellitus." in: Diabetes/metabolism research and reviews, Vol. 34, Issue 3, (2018) (PubMed).

Singh, Singh, Chandra, Tyagi: "Paraoxonase-1 is a better indicator than HDL of Atherosclerosis - A pilot study in North Indian population." in: Diabetes & metabolic syndrome, Vol. 12, Issue 3, pp. 275-278, (2018) (PubMed).

Synonyms and alternative names related to PON1

paraoxonase 2 (pon2), paraoxonase 1 (PON1), paraoxonase 1 (Pon1), esa, ESA, MGC53915, MGC89222, MVCD5, pon, PON, Pon, PON1, pon2

Protein level used designations for PON1

  • paraoxonase 1
  • paraoxonase 2
  • serum paraoxonase/arylesterase 1-like
  • A-esterase 1
  • K-45
  • PON 1
  • aromatic esterase 1
  • arylesterase B-type
  • esterase A
  • paraoxonase B-type
  • serum aryldiakylphosphatase
  • serum aryldialkylphosphatase 1
  • serum paraoxonase/arylesterase 1
  • serum paraoxonase
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