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POLR3G Proteins

(Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G))

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the RPC3/POLR3C-RPC6/POLR3F- RPC7/POLR3G subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

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POLR3G Protein (AA 44-104) (GST tag) (ABIN1315716)

POLR3G Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB

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Popular POLR3G Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

POLR3G Protein (AA 44-104) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1315716

Quantity 10 μg

Datasheet Datasheet

Aliases for POLR3G Proteins

polymerase (RNA) III (DNA directed) polypeptide G (Polr3g) Proteins
RNA polymerase III subunit G (POLR3G) Proteins
2310047G20Rik Proteins
AV275904 Proteins
RPC7 Proteins
RPC32 Proteins

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