Poliovirus Receptor Products
(Poliovirus Receptor (PVR))
Categories
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
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Featured Poliovirus Receptor Categories
Poliovirus Receptor Antibodies
High quality antibodies with extensive validation data.
Poliovirus Receptor ELISA Kits
Reliable ELISA kits for a wide range of species.
Poliovirus Receptor Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Poliovirus Receptor Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN7193491
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7443422
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
ELISA, FACS
Validations
- (3)
Cat. No.
ABIN7072567
Quantity
200 μg
Datasheet
Datasheet
Recommended Poliovirus Receptor ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958674
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4882138
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730099
Quantity
96 tests
Datasheet
Datasheet
Recommended Poliovirus Receptor Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7274081
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274075
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274071
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Poliovirus Receptor products
: "Nectin-2 Expression on Malignant Plasma Cells Is Associated with Better Response to TIGIT Blockade in Multiple Myeloma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 26, Issue 17, pp. 4688-4698, (2020) (PubMed).: "Trabectedin triggers direct and NK-mediated cytotoxicity in multiple myeloma." in: Journal of hematology & oncology, Vol. 12, Issue 1, pp. 32, (2019) (PubMed).
: "Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model." in: Scientific reports, Vol. 9, Issue 1, pp. 10840, (2019) (PubMed).
: "Low-dose bortezomib increases the expression of NKG2D and DNAM-1 ligands and enhances induced NK and γδ T cell-mediated lysis in multiple myeloma." in: Oncotarget, Vol. 8, Issue 4, pp. 5954-5964, (2018) (PubMed).
: "Validation of an Immunohistochemistry Assay for Detection of CD155, the Poliovirus Receptor, in Malignant Gliomas." in: Archives of pathology & laboratory medicine, Vol. 141, Issue 12, pp. 1697-1704, (2017) (PubMed).
: "Altered expression of CD226 and CD96 on natural killer cells in patients with pancreatic cancer." in: Oncotarget, Vol. 7, Issue 41, pp. 66586-66594, (2016) (PubMed).
: "Loss of DNAM-1 ligand expression by acute myeloid leukemia cells renders them resistant to NK cell killing." in: Oncoimmunology, Vol. 5, Issue 8, pp. e1196308, (2016) (PubMed).
: "Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia." in: Leukemia, Vol. 29, Issue 9, pp. 1799-810, (2015) (PubMed).
: "Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack. ..." in: Immunity, Vol. 42, Issue 2, pp. 344-55, (2015) (PubMed).
: "CD226 protein is involved in immune synapse formation and triggers Natural Killer (NK) cell activation via its first extracellular domain." in: The Journal of biological chemistry, Vol. 289, Issue 10, pp. 6969-77, (2014) (PubMed).
Synonyms and alternative names related to Poliovirus Receptor
poliovirus receptor (PVR), poliovirus receptor (Pvr), 3830421F03Rik, CD155, D7Ertd458e, HVED, mE4, Necl-5, necl-5, NECL5, PVR, PVS, Taa1, TAGE4, Tage4Protein level used designations for Poliovirus Receptor
- poliovirus receptor
- nectin-like 5
- nectin-like protein 5
- tumor-associated antigen 1
- tumor-associated glycoprotein pE4
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