POLD3 Products
(Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))
Categories
This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012].
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Featured POLD3 Categories
POLD3 Antibodies
High quality antibodies with extensive validation data.
POLD3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended POLD3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (4)
Cat. No.
ABIN6145881
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (4)
Cat. No.
ABIN7075130
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7263229
Quantity
200 μL
Datasheet
Datasheet
Recommended POLD3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6216202
Quantity
96 tests
Datasheet
Datasheet
Recommended POLD3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315628
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our POLD3 products
: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).: "Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells." in: DNA repair, Vol. 25, pp. 84-96, (2014) (PubMed).
: "Null mutations at the p66 and bradykinin 2 receptor loci induce divergent phenotypes in the diabetic kidney." in: American journal of physiology. Renal physiology, Vol. 303, Issue 12, pp. F1629-40, (2012) (PubMed).
: "Cellular DNA replicases: components and dynamics at the replication fork." in: Annual review of biochemistry, Vol. 74, pp. 283-315, (2005) (PubMed).
: "The human homologue of fission Yeast cdc27, p66, is a component of active human DNA polymerase delta." in: Journal of biochemistry, Vol. 129, Issue 5, pp. 699-708, (2001) (PubMed).
: "DNA polymerase delta, an essential enzyme for DNA transactions." in: Biological chemistry, Vol. 378, Issue 5, pp. 345-62, (1997) (PubMed).
Synonyms and alternative names related to POLD3
polymerase (DNA-directed), delta 3, accessory subunit L homeolog (pold3.L), polymerase (DNA-directed), delta 3, accessory subunit (pold3), DNA polymerase delta 3, accessory subunit (POLD3), polymerase (DNA-directed), delta 3, accessory subunit (Pold3), DNA polymerase delta 3, accessory subunit (Pold3), 2410142G14Rik, C85233, P66, P68, zgc:136471Protein level used designations for POLD3
- DNA-directed DNA polymerase delta 3
- DNA polymerase delta p66 subunit
- DNA polymerase delta subunit 3
- polymerase (DNA-directed), delta 3, accessory subunit
- DNA polymerase delta subunit 3-like
- DNA polymerase delta subunit p66
- Pol delta C subunit (p66)
- GC12
- polymerase (DNA directed), delta 3
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