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PODXL Products

(Podocalyxin-Like (PODXL))
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured PODXL Categories

PODXL Antibodies

High quality antibodies with extensive validation data.

PODXL ELISA Kits

Reliable ELISA kits for a wide range of species.

PODXL Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PODXL Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA, FACS, IP, IF
Validations
  • (9)
Cat. No. ABIN7163728
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rabbit, Rat
Application WB, IHC, FACS, IP, IF, StM
Validations
  • (6)
Cat. No. ABIN6940326
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (5)
Cat. No. ABIN7163724
Quantity 100 μg
Datasheet Datasheet

Recommended PODXL ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958666
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6974307
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969434
Quantity 96 tests
Datasheet Datasheet

Recommended PODXL Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124499
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124498
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN5854527
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our PODXL products

Wu, Xiong, Li, Yang, Ge et al.: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).

Riddell, Nakayama, Hikita, Mirzapourshafiyi, Kawamura, Pasha, Li, Masuzawa, Looso, Steinbacher, Ebnet, Potente, Hirose, Ohno, Fleming, Gattenlöhner, Aung, Phung, Yamasaki, Yanagi, Umemura, Nakayama: "aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability." in: Nature communications, Vol. 9, Issue 1, pp. 5357, (2019) (PubMed).

Harder, Menon, Otto, Zhou, Eddy, Wys, OConnor, Luo, Nair, Cebrian, Spence, Bitzer, Troyanskaya, Hodgin, Wiggins, Freedman, Kretzler: "Organoid single cell profiling identifies a transcriptional signature of glomerular disease." in: JCI insight, Vol. 4, Issue 1, (2019) (PubMed).

Hochane, van den Berg, Fan, Bérenger-Currias, Adegeest, Bialecka, Nieveen, Menschaart, Chuva de Sousa Lopes, Semrau: "Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development." in: PLoS biology, Vol. 17, Issue 2, pp. e3000152, (2019) (PubMed).

Christodoulou, Kyprianou, Weberling, Wang, Cui, Peng, Jing, Zernicka-Goetz: "Sequential formation and resolution of multiple rosettes drive embryo remodelling after implantation." in: Nature cell biology, Vol. 20, Issue 11, pp. 1278-1289, (2019) (PubMed).

Nilsson, Heglind, Arani, Enerbäck: "Foxc2 is essential for podocyte function." in: Physiological reports, Vol. 7, Issue 9, pp. e14083, (2019) (PubMed).

Genet, Boyé, Mathivet, Ola, Zhang, Dubrac, Li, Genet, Henrique Geraldo, Benedetti, Künzel, Pibouin-Fragner, Thomas, Eichmann: "Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis." in: Nature communications, Vol. 10, Issue 1, pp. 2350, (2019) (PubMed).

Dias, Kim, Holl, Werne Solnestam, Lundeberg, Carlén, Göritz, Frisén: "Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury." in: Cell, Vol. 173, Issue 1, pp. 153-165.e22, (2019) (PubMed).

Reiterer, Colaço, Emrouznejad, Jensen, Rundqvist, Johnson, Branco: "Acute and chronic hypoxia differentially predispose lungs for metastases." in: Scientific reports, Vol. 9, Issue 1, pp. 10246, (2019) (PubMed).

Diéguez-Hurtado, Kato, Giaimo, Nieminen-Kelhä, Arf, Ferrante, Bartkuhn, Zimmermann, Bixel, Eilken, Adams, Borggrefe, Vajkoczy, Adams: "Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes." in: Nature communications, Vol. 10, Issue 1, pp. 2817, (2019) (PubMed).

Synonyms and alternative names related to PODXL

podocalyxin like (PODXL), pyruvate carboxylase (PC), podocalyxin-like (Podxl), podocalyxin-like (podxl), pyruvate carboxylase (Pcx), podocalyxin like (Podxl), AW121214, cPCLP1, fc18d02, Gp135, Gp200, Ly102, MEP21, PC, Pc, PCB, Pcb, PCLP, PCLP-1, Pclp1, PCLP1, podocalyxin, PODXL, podxl, Podxl, wu:fc18d02

Protein level used designations for PODXL

  • GCTM-2 antigen
  • podocalyxin
  • podocalyxin-like protein 1
  • pyruvate carboxylase, mitochondrial
  • pyruvic carboxylase
  • thrombomucin
  • podocalyxin-like
  • PC-like protein 1
  • Podocalyxin-like protein 1
  • podocalyxin-like protein 1-like
  • pyruvate decarboxylase
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