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PNPLA3 Products

(Patatin-Like phospholipase Domain Containing 3 (PNPLA3))

Categories

The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes. [provided by RefSeq, Jul 2008].

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Featured PNPLA3 Categories

PNPLA3 Antibodies

High quality antibodies with extensive validation data.

PNPLA3 ELISA Kits

Reliable ELISA kits for a wide range of species.

PNPLA3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PNPLA3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (4)
  • (7)
Cat. No. ABIN361184
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN2783569
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN529283
Quantity 100 μg
Datasheet Datasheet

Recommended PNPLA3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958419
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958420
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Quantitative Competition ELISA
Validations
  • (3)
Cat. No. ABIN1979131
Quantity 96 tests
Datasheet Datasheet

Recommended PNPLA3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1315587
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409167
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409164
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PNPLA3 products

Yang, Mottillo, Mladenovic-Lucas, Zhou, Granneman: "Dynamic interactions of ABHD5 with PNPLA3 regulate triacylglycerol metabolism in brown adipocytes." in: Nature metabolism, Vol. 1, Issue 5, pp. 560-569, (2019) (PubMed).

Winberg, Motlagh, Stenkula, Holm, Jones: "Adiponutrin: a multimeric plasma protein." in: Biochemical and biophysical research communications, Vol. 446, Issue 4, pp. 1114-9, (2014) (PubMed).

Min, Sookoian, Pirola, Cheng, Mirshahi, Sanyal: "Metabolic profiling reveals that PNPLA3 induces widespread effects on metabolism beyond triacylglycerol remodeling in Huh-7 hepatoma cells." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 307, Issue 1, pp. G66-76, (2014) (PubMed).

Hao, Ito, Huang, Sae-tan, Lambert, Ross: "Shifts in dietary carbohydrate-lipid exposure regulate expression of the non-alcoholic fatty liver disease-associated gene PNPLA3/adiponutrin in mouse liver and HepG2 human liver cells." in: Metabolism: clinical and experimental, Vol. 63, Issue 10, pp. 1352-62, (2014) (PubMed).

Kumari, Schoiswohl, Chitraju, Paar, Cornaciu, Rangrez, Wongsiriroj, Nagy, Ivanova, Scott, Knittelfelder, Rechberger, Birner-Gruenberger, Eder, Brown, Haemmerle, Oberer, Lass, Kershaw, Zimmermann et al.: "Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase. ..." in: Cell metabolism, Vol. 15, Issue 5, pp. 691-702, (2012) (PubMed).

Gustavsson, Soga, Wahlström, Vesterlund, Azimi, Norstedt, Tollet-Egnell: "Sex-dependent hepatic transcripts and metabolites in the development of glucose intolerance and insulin resistance in Zucker diabetic fatty rats." in: Journal of molecular endocrinology, Vol. 47, Issue 2, pp. 129-43, (2011) (PubMed).

Steinberg, Kemp, Watt: "Adipocyte triglyceride lipase expression in human obesity." in: American journal of physiology. Endocrinology and metabolism, Vol. 293, Issue 4, pp. E958-64, (2007) (PubMed).

Johnson, Drugan, Miller, Evans: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)

Moldes, Beauregard, Faraj, Peretti, Ducluzeau, Laville, Rabasa-Lhoret, Vidal, Clément: "Adiponutrin gene is regulated by insulin and glucose in human adipose tissue." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 155, Issue 3, pp. 461-8, (2006) (PubMed).

Lake, Sun, Li, Kim, Johnson, Li, Revett, Shih, Liu, Paulsen, Gimeno: "Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members." in: Journal of lipid research, Vol. 46, Issue 11, pp. 2477-87, (2005) (PubMed).

Synonyms and alternative names related to PNPLA3

patatin like phospholipase domain containing 3 (PNPLA3), patatin-like phospholipase domain containing 3 (Pnpla3), ADPN, Adpn, C22orf20, iPLA(2)epsilon

Protein level used designations for PNPLA3

  • acylglycerol O-acyltransferase
  • adiponutrin
  • calcium-independent phospholipase A2-epsilon
  • iPLA2-epsilon
  • iPLA2epsilon
  • patatin-like phospholipase domain-containing protein 3
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