PNPLA1 Products
(Patatin-Like phospholipase Domain Containing 1 (PNPLA1))
Categories
The protein encoded by this gene belongs to the patatin-like phospholipase (PNPLA) family, which is characterized by the presence of a highly conserved patatin domain. PNPLA family members have diverse lipolytic and acyltransferase activities, and are key elements in lipid metabolism. While other members of this family have been well characterized, the function of this gene remained an enigma. However, recent studies show that this gene is expressed in the skin epidermal keratinocytes, and has a role in glycerophospholipid metabolism in the cutaneous barrier. Consistent with these observations, mutations in this gene are associated with ichthyosis in human (autosomal recessive congenital ichthyoses, ARCI) and dog. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012].
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Featured PNPLA1 Categories
PNPLA1 Antibodies
High quality antibodies with extensive validation data.
Recommended PNPLA1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7162688
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN949938
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN657271
Quantity
400 μL
Datasheet
Datasheet
Recommended PNPLA1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3086263
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3122279
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PNPLA1 products
: "PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans. ..." in: Nature genetics, Vol. 44, Issue 2, pp. 140-7, (2012) (PubMed).Synonyms and alternative names related to PNPLA1
patatin like phospholipase domain containing 1 (PNPLA1), patatin-like phospholipase domain containing 1 (Pnpla1), ARCI10, dJ50J22.1Protein level used designations for PNPLA1
- patatin-like phospholipase domain-containing protein 1
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