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PNMA1 Products

(Paraneoplastic Antigen MA1 (PNMA1))

Categories

The PNMA1 gene encodes an antineuronal antibody (anti-Ma) present in patients with paraneoplastic neurologic disorders (Dalmau et al., 1999 [PubMed 10050892]). Some paraneoplastic syndromes affecting the nervous system are associated with antibodies that react with neuronal proteins and the causal tumor (onconeuronal antigens) (summarized by Dalmau et al., 1999 [PubMed 10050892]). Several of these antibodies are markers of specific neurologic syndromes associated with distinct types of cancer. The presence of some antibodies is so specific that disorders previously identified by brain biopsy or at autopsy can be diagnosed serologically. The expression of neuronal proteins by the tumor appears to be a crucial step that breaks the immune tolerance for otherwise normal neuronal proteins. The identity of most onconeuronal antigens was established by probing human cDNA expression libraries with serum containing antineuronal antibodies.[supplied by OMIM, May 2010].

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Featured PNMA1 Categories

PNMA1 Antibodies

High quality antibodies with extensive validation data.

PNMA1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PNMA1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PNMA1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IP
Validations
  • (5)
Cat. No. ABIN522703
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (5)
Cat. No. ABIN563990
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN522702
Quantity 50 μg
Datasheet Datasheet

Recommended PNMA1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1147004
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1147006
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1147007
Quantity 96 tests
Datasheet Datasheet

Recommended PNMA1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124310
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315565
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315563
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PNMA1 products

Schüller, Jenne, Voltz: "The human PNMA family: novel neuronal proteins implicated in paraneoplastic neurological disease." in: Journal of neuroimmunology, Vol. 169, Issue 1-2, pp. 172-6, (2005) (PubMed).

Synonyms and alternative names related to PNMA1

PNMA family member 1 (PNMA1), paraneoplastic antigen MA1 (PNMA1), paraneoplastic antigen MA1 (Pnma1), paraneoplastic Ma antigen 1 (Pnma1), 5730402C15Rik, MA1, PNMA1

Protein level used designations for PNMA1

  • paraneoplastic antigen MA1
  • paraneoplastic antigen Ma1-like
  • paraneoplastic antigen Ma1 homolog
  • paraneoplastic onconeuronal protein MA1
  • 37 kDa neuronal protein
  • neuron- and testis-specific protein 1
  • paraneoplastic antigen Ma1
  • paraneoplastic neuronal antigen MA1
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