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PML Proteins

(Promyelocytic Leukemia (PML))

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions\; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

recommended

PML Protein (AA 411-510) (GST tag) (ABIN1315516)

PML Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

PML Protein (Transcript Variant 9) (Myc-DYKDDDDK Tag) (ABIN2729208)

PML Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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recommended

PML Protein (AA 59-239) (His tag) (ABIN7396061)

PML Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC

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PML Proteins by Origin

Find PML Proteins for a variety of species such as anti-Human PML, anti-Mouse PML. The species listed below are among those available. Click on a link to go to the corresponding products.

PML Proteins by Source

Here you will find PML Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

PML Proteins by Protein Type

Here you can find PML Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

PML Proteins by Application

Find PML Proteins validated for a specific application such as WB, AbP, ELISA, SDS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular PML Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

PML Protein (AA 411-510) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1315516

Quantity 10 μg

Datasheet Datasheet

PML Protein (Transcript Variant 9) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2729208

Quantity 20 μg

Datasheet Datasheet

PML Protein (AA 59-239) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7396061

Quantity 100 μg

Datasheet Datasheet

PML Protein (AA 1-882) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3094674

Quantity 1 mg

Datasheet Datasheet

PML Protein (AA 1-885) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3135325

Quantity 1 mg

Datasheet Datasheet

PML Protein (Transcript Variant 5) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2729209

Quantity 20 μg

Datasheet Datasheet

PML Protein (Transcript Variant 7) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2729210

Quantity 20 μg

Datasheet Datasheet

Latest Publications for our PML Proteins

Missiroli, Perrone, Gafà, Nicoli, Bonora, Morciano, Boncompagni, Marchi, Lebiedzinska-Arciszewska, Vezzani, Lanza, Kricek, Borghi, Fiorica, Ito, Wieckowski, Di Virgilio, Abelli, Pinton, Giorgi: "PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment." in: Cell death and differentiation, pp. 1-13, (2022) (PubMed).

Aliases for PML Proteins

promyelocytic leukemia (PML) Proteins
promyelocytic leukemia (Pml) Proteins
1200009E24Rik Proteins
AI661194 Proteins
MYL Proteins
PML Proteins
PP8675 Proteins
RGD1562602 Proteins
RNF71 Proteins
TRIM19 Proteins
Trim19 Proteins

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PML Proteins by Origin

PML Proteins by Source

PML Proteins by Protein Type

PML Proteins by Application

Popular PML Proteins

Latest Publications for our PML Proteins

Aliases for PML Proteins

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