PLCE1 Products
(Phospholipase C, epsilon 1 (PLCE1))
Categories
This gene encodes a phospholipase enzyme that catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to generate two second messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). These second messengers subsequently regulate various processes affecting cell growth, differentiation, and gene expression. This enzyme is regulated by small monomeric GTPases of the Ras and Rho families and by heterotrimeric G proteins. In addition to its phospholipase C catalytic activity, this enzyme has an N-terminal domain with guanine nucleotide exchange (GEF) activity. Mutations in this gene cause early-onset nephrotic syndrome\; characterized by proteinuria, edema, and diffuse mesangial sclerosis or focal and segmental glomerulosclerosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009].
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Featured PLCE1 Categories
PLCE1 Antibodies
High quality antibodies with extensive validation data.
PLCE1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PLCE1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
IHC, WB, IP, ICC
Validations
- (3)
Cat. No.
ABIN7445363
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
IHC, WB, IP, ICC
Validations
- (2)
Cat. No.
ABIN7445360
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
IHC, WB, ELISA
Validations
- (2)
Cat. No.
ABIN6257434
Quantity
100 μL
Datasheet
Datasheet
Recommended PLCE1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422847
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7420075
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7420078
Quantity
100 μg
Datasheet
Datasheet
Synonyms and alternative names related to PLCE1
phospholipase C, epsilon 1 (PLCE1), phospholipase C epsilon 1 (PLCE1), phospholipase C, epsilon 1 (plce1), phospholipase C epsilon 1 (plce1), phospholipase C, epsilon 1 (Plce1), 4933403A21Rik, mKIAA1516, NPHS3, PLCE, Plce, PLCE1, PLCepsilon, PPLCProtein level used designations for PLCE1
- phospholipase C, epsilon 1
- pancreas-enriched phospholipase C
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1-like
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
- PLC-epsilon-1
- phosphoinositide phospholipase C-epsilon-1
- phosphoinositide-specific phospholipase C epsilon-1
- phospholipase C-epsilon-1
- phospholipase C epsilon
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