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(Phospholipase C (PLC))
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Constitutes an essential virulence factor in gas gangrene. Binds to eukaryotic membranes where it hydrolyzes both phosphatidylcholine and sphingomyelin. The diacylglycerol produced can activate both the arachidonic acid pathway, leading to modulation of the inflammatory response cascade and thrombosis, and protein kinase C, leading to activation of eukaryotic phospholipases and further membrane damage. Acts on human and mouse erythrocytes, but not on rabbit or horse erythrocytes.

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Featured PLC Categories

PLC Antibodies

High quality antibodies with extensive validation data.

PLC ELISA Kits

Reliable ELISA kits for a wide range of species.

PLC Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PLC Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Bacillus cereus
Application WB, IF, ELISA
Validations
Cat. No. ABIN459259
Quantity 10 mg
Datasheet Datasheet
Reactivity Bacillus cereus
Application WB, IF, ELISA
Validations
Cat. No. ABIN459094
Quantity 1 mL
Datasheet Datasheet
Reactivity Bacillus cereus
Application WB, IF, ELISA, IHC
Validations
Cat. No. ABIN958867
Quantity 1 mL
Datasheet Datasheet

Recommended PLC ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rabbit
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN775589
Quantity 96 tests
Datasheet Datasheet
Reactivity Guinea Pig
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN777554
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN772333
Quantity 96 tests
Datasheet Datasheet

Recommended PLC Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Bacillus cereus
Source Yeast
Validations
Cat. No. ABIN1666745
Quantity 1 mg
Datasheet Datasheet
Reactivity Clostridium perfringens
Source Yeast
Validations
Cat. No. ABIN1653987
Quantity 1 mg
Datasheet Datasheet

Synonyms and alternative names related to PLC

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (plc-1), 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II (LOC408791), phospholipase C (PLC), phospholipase C1 (PLC1), phospholipase C (plc), phospholipase C (plC), uncharacterized LOC100851276 (LOC100851276), phospholipase C (LOC100009319), ARABIDOPSIS THALIANA PHOSPHOLIPASE C, ATPLC, ATPLC1, BA0677, BCE0744, GB16555, MZN1.12, MZN1_12, PHOSPHOLIPASE C, phospholipase C 1, phospholipase C1, PLC

Protein level used designations for PLC

  • PhosphoLipase C family member (plc-1)
  • phospholipase C
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