Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Products
(Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))
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This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009].
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Featured Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Categories
Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Antibodies
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Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) ELISA Kits
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Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC
Validations
- (5)
Cat. No.
ABIN184751
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN518586
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN7269401
Quantity
100 μL
Datasheet
Datasheet
Recommended Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969386
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1148326
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1148327
Quantity
96 tests
Datasheet
Datasheet
Recommended Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313891
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313893
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3134596
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) products
: "Chronic exposure of adult rats to low doses of methylmercury induced a state of metabolic deficit in the somatosensory cortex." in: Journal of proteome research, Vol. 12, Issue 11, pp. 5233-45, (2013) (PubMed).: "Overexpression of PAFAH1B1 is associated with tumor metastasis and poor survival in non-small cell lung cancer." in: Lung cancer (Amsterdam, Netherlands), Vol. 77, Issue 3, pp. 585-92, (2012) (PubMed).
: "Human mutations in NDE1 cause extreme microcephaly with lissencephaly [corrected]." in: American journal of human genetics, Vol. 88, Issue 5, pp. 536-47, (2011) (PubMed).
: "Functional interplay between LIS1, NDE1 and NDEL1 in dynein-dependent organelle positioning." in: Journal of cell science, Vol. 123, Issue Pt 2, pp. 202-12, (2010) (PubMed).
: "DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 1, pp. 15-26, (2007) (PubMed).
: "Neuronal migration in developmental disorders." in: Journal of child neurology, Vol. 20, Issue 4, pp. 280-6, (2005) (PubMed).
: "APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment." in: Molecular biology of the cell, Vol. 16, Issue 10, pp. 4609-22, (2005) (PubMed).
: "LIS2, gene and pseudogene, homologous to LIS1 (lissencephaly 1), located on the short and long arms of chromosome 2." in: Genomics, Vol. 30, Issue 2, pp. 251-6, (1996) (PubMed).
: "Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase [corrected]." in: Nature, Vol. 370, Issue 6486, pp. 216-8, (1994) (PubMed).
: "Isolation of a Miller-Dieker lissencephaly gene containing G protein beta-subunit-like repeats." in: Nature, Vol. 364, Issue 6439, pp. 717-21, (1993) (PubMed).
Synonyms and alternative names related to Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa)
platelet activating factor acetylhydrolase 1b regulatory subunit 1 (PAFAH1B1), platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 (Pafah1b1), platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (Pafah1b1), platelet activating factor acetylhydrolase 1b regulatory subunit 1 L homeolog (pafah1b1.L), platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a (pafah1b1a), platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b (pafah1b1b), platelet activating factor acetylhydrolase 1b regulatory subunit 1 (Pafah1b1), LIS-1, LIS1, Lis1, Lis1a, LIS2, lis2, MDCR, mdcr, MDS, mds, Mdsh, MMS10-U, Ms10u, PAFAH, pafah, pafah1b1-b, Pafaha, PAFAHAProtein level used designations for Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa)
- LIS-1
- PAF acetylhydrolase 45 kDa subunit
- PAF-AH 45 kDa subunit
- PAF-AH alpha
- PAFAH alpha
- lissencephaly 1 protein
- lissencephaly-1 protein
- platelet-activating factor acetylhydrolase IB subunit alpha
- platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD)
- platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)
- platelet-activating factor acetylhydrolase 1b, regulatory subunit 1
- platelet-activating factor acetylhydrolase, isoform 1b, beta1 subunit
- PAF-AH beta
- platelet-activating factor acetylhydrolase beta subunit (PAF-AH beta)
- platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
- platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa
- LIS1
- lissencephaly-1 homolog
- lissencephaly-1 homolog B
- chLIS1
- platelet-activating factor acetylhydrolase Ib-alpha subunit
- Miller-Dieker syndrome chromosome region
- Lissencephaly-1 protein
- platelet-activating factor acetylhydrolase isoform Ib alpha subunit
- lis1b
- lissencephaly-1 homolog A
- platelet-activating factor acetylhydrolase IB subunit alpha a
- platelet-activating factor acetylhydrolase IB subunit alpha b
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